tert-Butyl (2-bromo-5-methylpyridin-4-yl)carbamate CAS 1935168-99-2
| CAS No. | 1935168-99-2 |
| Molecular Formula | C11H15BrN2O2 |
| Molecular Weight | 287.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl (2-bromo-5-methylpyridin-4-yl)carbamate.
CATO supplies tert-Butyl (2-bromo-5-methylpyridin-4-yl)carbamate (CAS 1935168-99-2), a certified reference material (molecular formula C11H15BrN2O2, MW 287.15 g/mol) for analytical method development and quality control.
The molecular framework of tert-Butyl (2-bromo-5-methylpyridin-4-yl)carbamate (C11H15BrN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H15BrN2O2 |
| Molecular Weight | 287.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Tert-butyl (4-(bromomethyl)pyridin-2-yl)carbamate (CAS 190189-98-1)
- (S)-5-Bromo-N-(3-hydroxy-3-methylbutan-2-yl)picolinamide (CAS 1956435-64-5)
- tert-Butyl (6-bromo-5-methylpyridin-3-yl)carbamate (CAS 1880630-79-4)
- (2-Amino-4-bromo-phenyl)-carbamic acid tert-butyl ester (CAS 954239-15-7)
- 1-(4-Bromophenyl)cyclohexan-1-amine (CAS 1094442-21-3)
- 4-Bromobenzo[d]oxazole-2-carboxylic acid (CAS 944907-35-1)
- 2-C-Methylguanosine (CAS 374750-30-8)
- 5-Fluoro-2-(trifluoromethoxy)benzoic acid (CAS 1092460-83-7)
- N,N'-(pyridazine-3,6-diyl)bis(4-aminobenzenesulfonamide) (CAS CATO-C3D-263249)
- 4-Fluoro-3-(methanesulfonyl)phenylboronic acid (CAS 1268496-35-0)
- (1S,2S)-2-fluorocyclopropan-1-amine hydrochloride (CAS 1638744-20-3)
- (S)-2-((S)-2,2-Diphenyl-1,3-dioxolan-4-yl)piperidine (CAS 4741-41-7)
- N-{2-[(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)amino]pyridin-3-yl}-4-methylbenzamide (CAS 338772-61-5)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
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