Posaconazole Impurity 128 CAS 1941207-64-2
| CAS No. | 1941207-64-2 |
| Molecular Formula | C19H24O4S |
| Molecular Weight | 348.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Posaconazole Impurity 128.
As a process- or degradation-related impurity, Posaconazole Impurity 128 (CAS 1941207-64-2, C19H24O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Posaconazole Impurity 128 (C19H24O4S) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Posaconazole Impurity 128 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H24O4S |
| Molecular Weight | 348.46 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Sulfur Atoms | 1 |
Related Posaconazole Standards
- Posaconazole impurity 244 (CAS CATO-C4X-1208244)
- Posaconazole impurity 211 (CAS CATO-C4X-1208211)
- Posaconazole impurity 212 (CAS CATO-C4X-1208212)
- Posaconazole impurity 213 (CAS CATO-C4X-1208213)
- Posaconazole impurity 214 (CAS CATO-C4X-1208214)
- Posaconazole Impurity 202 (CAS CATO-C4X-1208202)
- Posaconazole Impurity 75 (CAS CATO-C4X-120875)
- Posaconazole Methoxy Nitro Impurity (CAS 1246819-65-7)
Recommended Standards
- Tamsulosin Impurity 78 (CAS CATO-C4X-118778)
- Tamsulosin Impurity 61 (CAS 2458209-31-7)
- Erdosteine Impurity 8 (CAS CATO-C4X-19638)
- Tamsulosin Impurity 60 (CAS 1537178-25-8)
- Dotinurad Impurity 155 (CAS CATO-C4X-2494155)
- Cinacalcet Impurity 37 (CAS 100485-59-4)
- N-Nitroso Nafamostat impurity 121 HCl (CAS CATO-C4X-1332121)
- ethyl 3,5-dichloro-1,2,4-triazine-6-carboxylate (CAS 1629760-05-9)
- (2S,3S)-methyl 3-aminobicyclo[2.2.2]octane-2-carboxylate hydrochloride (CAS 2173637-41-5)
- Fmoc-Glu(allyl ester)-OH (CAS 133464-46-7)
- Iopamidol EP Impurity G (CAS 1869069-72-6)
- 5-Methoxy-2-methyl-1H-indole-3-carbaldehyde (CAS 6260-86-2)
- Delucemine HCl (CAS 186495-99-8)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com