methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyridine-3-carboxylate CAS 1942057-11-5
| CAS No. | 1942057-11-5 |
| Molecular Formula | C21H33BN2O5Si |
| Molecular Weight | 432.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyridine-3-carboxylate is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyridine-3-carboxylate (CAS 1942057-11-5), molecular formula C21H33BN2O5Si and molecular weight 432.39 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-trimethylsilylethoxymethyl)pyrrolo[2,3-b]pyridine-3-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 432.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H33BN2O5Si |
| Molecular Weight | 432.39 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 2 |
Related methyl Standards
- 4,4,5,5-Tetramethyl-2-(5'-phenyl-[1,1':3',1''-terphenyl]-3-yl)-1,3,2-dioxaborolane (CAS 1257248-43-3)
- 2,7-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-fluoren-9-one (CAS 1116122-63-4)
- N-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)phenyl)-4-(trifluoromethyl)pyrimidin-2-amine (CAS 1312535-12-8)
- 1-{[2,5-Bis(tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-3-yl]carbonyl}pyrrolidine (CAS 2377607-12-8)
- 78140-47-3 2,2,6,6-Tetramethyl-4-[(triphenyl-lambda~5~-phosphanylidene)amino]piperidin-1-ol DTXSID80676262 (CAS 78140-47-3)
- 2-((4-Oxo-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydrophthalazin-1-yl)methyl)isoindoline-1,3-dione (CAS 2629316-44-3)
- 1,2-Bis[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]diazene (CAS 1432792-09-0)
- 1,2-bis(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethane (CAS 1422172-96-0)
Recommended Standards
- 4-Fluoro-3-((4-hydroxypiperidin-1-yl)sulfonyl)-N-(3,4,5-trifluorophenyl)benzamide (CAS 1445790-55-5)
- 1-((4-Fluorophenyl)sulfonyl)-N-(4-(trifluoromethoxy)phenyl)pyrrolidine-2-carboxamide (CAS 317377-84-7)
- 6-Morpholin-4-yl-3-nitro-4-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2]bipyridinyl-4-carboxylic acid ethyl ester (CAS 1089330-49-3)
- 2-(2-((3aS,6aS)-5-(2-Methoxyphenyl)-4,6-dioxo-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrazol-3-yl)-2-oxoethyl)isoindoline-1,3-dione (CAS 956934-85-3)
- 951887-46-0 2-Chloro-4-(2-naphthyl)-1-butene MFCD09801379 (CAS 951887-46-0)
- n-(2-(Pyridin-2-yl)ethyl)furan-2-carboxamide (CAS 1209087-53-5)
- 5,5-Dimethylocta-2,7-diynoic acid (CAS 500596-39-4)
- 4-{[3-(dimethylamino)propyl]amino}-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 685109-23-3)
- Clofarabine (CAS 123318-82-1)
- Deflazacort 21-Formate (CAS CATO-C4X-233613)
- 2-(Chloromethyl)-3-(difluoromethyl)-5-iodopyridine-6-carboxaldehyde (CAS 1807153-39-4)
- 6-Bromo-2-methylpyrido[2,3-d]pyrimidin-4(3H)-one (CAS 1361459-59-7)
- Desipramine Impurity 1 (CAS 1977-15-7)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
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