5-Chlorovanillin CAS 19463-48-0
| CAS No. | 19463-48-0 |
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chlorovanillin.
CATO supplies 5-Chlorovanillin (CAS 19463-48-0), a certified reference material (molecular formula C8H7ClO3, MW 186.59 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chlorovanillin (C8H7ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chlorovanillin meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
Related Chlorovanillin Standards
Recommended Standards
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- Sulforhodamine 101 DHPE (CAS 187099-99-6)
- 2-Bromobutane (CAS 78-76-2)
- 1-(1-Methoxycyclopropyl)-N-methylmethanamine (CAS 1638772-10-7)
- 5-(Aminomethyl)-2H-tetrazole (CAS 31602-63-8)
- Ethyl 4-iodo-3,5-dimethylbenzoate (CAS 1048677-10-6)
- tert-butyl 5-(bromomethyl)indole-1-carboxylate (CAS 442685-53-2)
- ACTB-1003 (CAS 939805-30-8)
- (2,5-Dimethylphenyl)(phenyl)methanethiol (CAS 1039935-15-3)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
Why CATO?
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