(R)-1-(6-(trifluoromethyl)pyridazin-3-yl)ethan-1-amine hydrochloride CAS 1948236-91-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1948236-91-6
Molecular FormulaC7H8F3N3
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(R)-1-(6-(trifluoromethyl)pyridazin-3-yl)ethan-1-amine hydrochloride CAS 1948236-91-6 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-1-(6-(trifluoromethyl)pyridazin-3-yl)ethan-1-amine hydrochloride.

(R)-1-(6-(trifluoromethyl)pyridazin-3-yl)ethan-1-amine hydrochloride (CAS 1948236-91-6), molecular formula C7H8F3N3HCl and molecular weight 227.61 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (R)-1-(6-(trifluoromethyl)pyridazin-3-yl)ethan-1-amine hydrochloride (C7H8F3N3HCl) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H8F3N3 HCl
Molecular Weight227.61 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1996
Halogen ContentF/Cl-containing
Nitrogen Atoms3

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