5-Fluorobenzo[c]isoxazole-3-carbonitrile CAS 194873-12-6
| CAS No. | 194873-12-6 |
| Molecular Formula | C8H3FN2O |
| Molecular Weight | 162.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Fluorobenzo[c]isoxazole-3-carbonitrile (C8H3FN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 5-Fluorobenzo[c]isoxazole-3-carbonitrile (CAS 194873-12-6), a certified reference material (molecular formula C8H3FN2O, MW 162.12 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Fluorobenzo[c]isoxazole-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H3FN2O |
| Molecular Weight | 162.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorobenzo Standards
- 4-Fluorobenzo[d]oxazole-2-carbonitrile (CAS 1172606-57-3)
- 6-Fluorobenzo[d]isoxazole-3-carbonitrile (CAS 1314937-26-2)
- 6-Fluorobenzo[c]isoxazole-3-carbonitrile (CAS 23073-23-6)
- 6-Fluorobenzo[e][1,2,4]triazin-3-amine (CAS 680180-41-0)
- 7-Fluorobenzo[e][1,2,4]triazin-3-amine (CAS 74916-44-2)
- 6-Fluorobenzo[d][1,2,3]triazin-4(1H)-one (CAS 1008742-31-1)
- 7-Fluorobenzo[d][1,2,3]triazin-4(1H)-one (CAS 1436850-60-0)
- 6-Fluorobenzo[d]isoxazole-3-carbaldehyde (CAS 1824114-20-6)
Recommended Standards
- 5-Fluoro-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 187837-96-3)
- 1-Methoxyphosphinan-4-one 1-oxide (CAS 57384-32-4)
- Dimethyl 2-fluorofumarate (CAS 18414-17-0)
- 4-fluoro-2-isocyanatobenzonitrile (CAS 923255-70-3)
- Ethyl 4-(4-chlorophenyl)-5-formyl-2-methyl-6-(pyridin-2-ylsulfanyl)-1,4-dihydropyridine-3-carboxylate (CAS 478261-90-4)
- 2-(2-(((3-Cyclohexyl-5-thioxo-1H-1,2,4-triazol-4(5H)-yl)imino)methyl)phenoxy)acetic acid (CAS 478253-65-5)
- tert-Butyl 3-(4-fluorophenyl)piperazine-1-carboxylate (CAS 886767-25-5)
- 2-(Difluoromethyl)-6-hydroxypyridine-3-carboxamide (CAS 1805313-01-2)
- 1-(2,3-Dimethylphenyl)-piperazine (CAS 1013-22-5)
- 2-chloroethyl diethyl phosphate (CAS 5630-71-7)
- 3,4-Diamino-1-methylquinolin-2(1H)-one (CAS 921214-45-1)
- 5,6-Dihydroquinolin-5-ol (CAS 160240-11-9)
- 1,4-Dimethoxy-2-nitro-3-[(E)-2-nitroethenyl]benzene (CAS 143814-63-5)
- KALA Amphipathic Peptide (CAS 187987-64-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com