1-{1H-pyrrolo[2,3-b]pyridine-6-carbonyl}-4-(2,2,2-trifluoroethyl)piperazine CAS 1952123-25-9
| CAS No. | 1952123-25-9 |
| Molecular Formula | C14H15F3N4O |
| Molecular Weight | 312.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-{1H-pyrrolo[2,3-b]pyridine-6-carbonyl}-4-(2,2,2-trifluoroethyl)piperazine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-{1H-pyrrolo[2,3-b]pyridine-6-carbonyl}-4-(2,2,2-trifluoroethyl)piperazine (CAS 1952123-25-9) is a high-purity analytical reference standard with the molecular formula C14H15F3N4O and a molecular weight of 312.29 g/mol.
The molecular framework of 1-{1H-pyrrolo[2,3-b]pyridine-6-carbonyl}-4-(2,2,2-trifluoroethyl)piperazine (C14H15F3N4O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-{1H-pyrrolo[2,3-b]pyridine-6-carbonyl}-4-(2,2,2-trifluoroethyl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H15F3N4O |
| Molecular Weight | 312.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related H Standards
- (1-{1H-pyrrolo[2,3-b]pyridine-4-carbonyl}-3-(trifluoromethyl)pyrrolidin-3-yl)methanol (CAS 2406259-86-5)
- Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-ethyl ester (CAS 2408430-30-6)
- N-(4-(pyrrolo[1,2-a]quinoxalin-4-yloxy)phenyl)acetamide (CAS 477886-72-9)
- 1H-Pyrrolo[2,3-b]pyridine-4-carboxaldehyde, 1-[tris(1-methylethyl)silyl]- (CAS 916259-53-5)
- 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 1-(phenylsulfonyl)- (CAS 245064-80-6)
- Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid, 3-amino-4,6-dihydro-6,6-dimethyl-1-(1-oxopropoxy)-, 1,1-dimethylethyl ester (CAS 2007915-99-1)
- Pyrrolo[3,4-c]pyrazole-5(4H)-carboxylic acid, 3-amino-2,6-dihydro-6,6-dimethyl-2-(1-oxopropoxy)-, 1,1-dimethylethyl ester (CAS 2007916-02-9)
- 1-{1H-pyrrolo[2,3-b]pyridine-6-carbonyl}-4-(1,1,1-trifluoropropan-2-yl)piperazine (CAS 1947752-82-0)
Recommended Standards
- tert-Butyl (8-(trifluoromethyl)quinolin-3-yl)carbamate (CAS 1447607-03-5)
- Ethyl 2-(5-methyl-3-(3-(trifluoromethyl)phenyl)-1H-pyrazol-1-yl)acetate (CAS 1956380-60-1)
- Ethyl 4-(dimethylamino)-6-(trifluoromethyl)quinoline-3-carboxylate (CAS 1216463-17-0)
- (3S,5R)-3-Hydroxy-5-(2,2,2-trifluoro-acetylamino)-piperidine-1-carboxylic acid tert-butyl ester (CAS 2331211-40-4)
- 2-Methoxy-5-(pyridin-4-yl)aniline (CAS 104994-92-5)
- Ethyl 2-methyl-5-(phenylsulfonamido)benzofuran-3-carboxylate (CAS 412300-79-9)
- (S)-6-Bromo-1-(sec-butyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-1H-indole-4-carboxamide (CAS 1346574-54-6)
- 2-(2-Methyl-1,3-dioxolan-2-yl)acetic acid (CAS 5735-97-7)
- (S)-2-BENZYLPYRROLIDINE HCL (CAS 144889-08-7)
- 4-(3-Chlorophenyl)-2-butanone (CAS 3506-73-8)
- 1-(2,5-Dimethoxyphenyl)-5-(5,5-dimethyl-1,3-dioxan-2-yl)pentan-1-one (CAS 898756-13-3)
- 2-(2-Methoxyethoxy)acetamide (CAS 200617-05-6)
- tert-Butyl 4-(5-bromo-2-chlorobenzyl)piperazine-1-carboxylate (CAS 1704074-43-0)
- Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 75976-10-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com