Perindopril Impurity 117 CAS 19522-25-9
| CAS No. | 19522-25-9 |
| Molecular Formula | C11H10O3 |
| Molecular Weight | 190.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Perindopril Impurity 117 (CAS 19522-25-9) is a certified pharmaceutical impurity reference standard with the molecular formula C11H10O3 and a molecular weight of 190.20 g/mol.
The molecular framework of Perindopril Impurity 117 (C11H10O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Perindopril Impurity 117 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10O3 |
| Molecular Weight | 190.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
Related Perindopril Standards
- Perindopril Impurity 104 (CAS CATO-C4X-1252104)
- Perindopril Impurity 105 (CAS 760127-31-9)
- Perindopril Impurity 47 (CAS 192436-84-3)
- Perindopril Impurity 34 (CAS CATO-C4X-125234)
- Perindopril Impurity 103 (CAS CATO-C4X-1252103)
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- Perindopril Impurity 110 (CAS 145438-94-4)
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