2-(((4-Fluorophenyl)amino)methylene)malononitrile CAS 195243-31-3
| CAS No. | 195243-31-3 |
| Molecular Formula | C10H6FN3 |
| Molecular Weight | 187.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(((4-Fluorophenyl)amino)methylene)malononitrile (C10H6FN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-(((4-Fluorophenyl)amino)methylene)malononitrile (CAS 195243-31-3) is a high-purity analytical reference standard with the molecular formula C10H6FN3 and a molecular weight of 187.17 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6FN3 |
| Molecular Weight | 187.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- 1-(4-Fluorophenyl)-1H-pyrazole-4-carbonitrile (CAS 1015862-36-8)
- 2-(((2-Fluorophenyl)amino)methylene)malononitrile (CAS 910418-34-7)
- 3-(4-Fluorophenyl)aniline (CAS 10540-45-1)
- 2-(2-Fluorophenyl)-4-methylpyridine (CAS 886444-12-8)
- 2-(4-Fluorophenyl)-4-methylpyridine (CAS 222551-24-8)
- 2-(4-Fluorophenyl)-5-methylpyridine (CAS 85237-65-6)
- 5-(3-Fluorophenyl)-2-methylpyridine (CAS 713143-67-0)
- N-(4-fluorophenyl)-N-methylcarbamoyl chloride (CAS 55239-51-5)
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- 5-(Methoxycarbonyl)thiazole-4-carboxylic acid (CAS 1894393-14-6)
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- (E)-2-(3-Methyl-2,4-dioxothiazolidin-5-ylidene)acetic acid (CAS 90137-11-4)
- 3-(2-Bromo-4,5-dimethoxyphenyl)propanoicacid (CAS 52679-49-9)
- 3-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-benzaldehyde O-methyl-oxime (CAS 1311283-85-8)
- 2-Cyclopentyl-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 1850834-94-4)
- n-Acetyl-n-(prop-2-yn-1-yl)glycine (CAS 1515118-47-4)
- 7,9-Bis(2,6-bis((R)-1-(3,5-di-tert-butylphenyl)ethyl)-4-methylphenyl)-7H-acenaphtho[1,2-d]imidazol-9-ium chloride (CAS 2212005-59-7)
- 2-(Chloromethyl)-4h-3,1-benzoxazin-4-one (CAS 98592-35-9)
- N-((3,5-dimethylisoxazol-4-yl)methyl)methanesulfonamide (CAS 1485538-81-5)
- (6-(Tert-pentyl)-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)methanamine (CAS 1019351-98-4)
- 2-(2-Bromo-4-chlorophenoxy)-N-methoxypropanamide (CAS 1031042-86-0)
- Hexapeptide-1 (CAS CATO-CPTD788821)
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