Ceftolozane impurity 2 CAS 1956303-46-0
| CAS No. | 1956303-46-0 |
| Molecular Formula | C26H42N14O8S2 |
| Molecular Weight | 742.83 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Ceftolozane impurity 2 (CAS 1956303-46-0), a pharmacopoeial impurity reference standard (molecular formula C26H42N14O8S2, MW 742.83 g/mol) used for the identification and quantification of trace impurities in APIs.
Ceftolozane impurity 2 (C26H42N14O8S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H42N14O8S2 |
| Molecular Weight | 742.83 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 14 |
| Sulfur Atoms | 2 |
Related Ceftolozane Standards
- Ceftolozane Impurity 21 (CAS CATO-C4X-240621)
- Ceftolozane Impurity 31 (CAS CATO-C4X-240631)
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