Ceftolozane Impurity 17 CAS CATO-C4X-240617
| CAS No. | CATO-C4X-240617 |
| Molecular Formula | C28H33ClN6O8S2 |
| Molecular Weight | 681.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ceftolozane Impurity 17 (CAS CATO-C4X-240617, C28H33ClN6O8S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ceftolozane Impurity 17 (C28H33ClN6O8S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H33ClN6O8S2 |
| Molecular Weight | 681.18 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Ceftolozane Standards
- Ceftolozane Impurity 20 (CAS CATO-C4X-240620)
- Ceftolozane Impurity 42 (CAS CATO-C4X-240642)
- Ceftolozane Impurity 34 (CAS CATO-C4X-240634)
- Ceftolozane Impurity 35 (CAS CATO-C4X-240635)
- Ceftolozane (CAS 689293-68-3)
- Ceftolozane impurity 7 (CAS 1956303-45-9)
- Ceftolozane impurity 8 (CAS 1956303-44-8)
- Ceftolozane impurity 9 (CAS 1852466-67-1)
Recommended Standards
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- Diarachidin (CAS 60586-60-9)
- 4-Fluoro-3,5-bis(tributylstannyl)pyridine (CAS 1204580-75-5)
- Cefdinir Impurity 54 (CAS CATO-C4X-121054)
- Lenvatinib Impurity 10 (CAS 97480-55-2)
- Lansoprazole Impurity 48 (CAS CATO-C4X-161248)
- Mirogabalin Impurity 10 (CAS CATO-C4X-292410)
- (S)-N2-(1-Benzylpyrrolidin-3-yl)pyridine-2,3-diamine (CAS 1421013-61-7)
- 2,4,8-Trimethyl-5,6,7,8-tetrahydroquinoline (CAS 809241-38-1)
- methyl 3-methyl-1,2,4-thiadiazole-5-carboxylate (CAS 352356-71-9)
- Edoxaban Impurity 40 (1S,2R,4S) Mesylate (CAS 1807315-98-5)
- 3-Chloro-4-((4-chlorobenzyl)oxy)benzohydrazide (CAS 1706445-94-4)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
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