1-[(tert-Butyldiphenylsilyl)oxy]-3-chloro-2-propanone CAS 1956332-66-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1956332-66-3
Molecular FormulaC19H23ClO2Si
Molecular Weight346.92 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-[(tert-Butyldiphenylsilyl)oxy]-3-chloro-2-propanone CAS 1956332-66-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[(tert-Butyldiphenylsilyl)oxy]-3-chloro-2-propanone.

CATO supplies 1-[(tert-Butyldiphenylsilyl)oxy]-3-chloro-2-propanone (CAS 1956332-66-3), a certified reference material (molecular formula C19H23ClO2Si, MW 346.92 g/mol) for analytical method development and quality control.

The molecular framework of 1-[(tert-Butyldiphenylsilyl)oxy]-3-chloro-2-propanone (C19H23ClO2Si) is characterized by a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-[(tert-Butyldiphenylsilyl)oxy]-3-chloro-2-propanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC19H23ClO2Si
Molecular Weight346.92 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1996
Halogen ContentCl-containing

Related tert Standards

Recommended Standards

Why CATO?