7-Bromo-4-chloro-6-fluoroquinazoline CAS 1956334-41-0
| CAS No. | 1956334-41-0 |
| Molecular Formula | C8H3BrClFN2 |
| Molecular Weight | 261.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-Bromo-4-chloro-6-fluoroquinazoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 7-Bromo-4-chloro-6-fluoroquinazoline (CAS 1956334-41-0), a certified reference material (molecular formula C8H3BrClFN2, MW 261.48 g/mol) for analytical method development and quality control.
7-Bromo-4-chloro-6-fluoroquinazoline (C8H3BrClFN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H3BrClFN2 |
| Molecular Weight | 261.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 6-Bromo-2-chloro-5-fluoroquinazoline, 97% (CAS 1036756-07-6)
- 8-Bromo-4-chloro-5-fluoroquinazoline (CAS 1351499-20-1)
- 8-Bromo-4-chloro-6-fluoroquinazoline (CAS 1351499-77-8)
- 5-Bromo-4-chloro-8-fluoroquinazoline (CAS 1564693-03-3)
- 6-Bromo-4-chloro-8-fluoroquinazoline (CAS 1565583-08-5)
- 5-Bromo-2-chloro-7-fluoroquinoxaline (CAS 1881290-86-3)
- 7-Bromo-2-chloro-6-fluoroquinoxaline (CAS 1881295-54-0)
- 2-Bromo-8-chloro-6-fluoroquinazoline (CAS 2089334-70-1)
Recommended Standards
- 2-(Dimethyl(non-1-en-4-yl)silyl)pyridine (CAS 358782-90-8)
- 3,4-Dichloro-2-(difluoromethoxy)benzyl chloride (CAS 1807184-91-3)
- 5-Bromo-8-chloro-3-fluoro-1,7-naphthyridine (CAS 2167672-12-8)
- 2,5-Dichloro-3-(difluoromethoxy)benzyl chloride (CAS 1807184-86-6)
- (S)-5-Butyl-3-phenyl-2-thioxoimidazolidin-4-one (CAS 56710-94-2)
- 4-Bromo-3-(trifluoromethyl)phenylacetic Acid (CAS 914637-17-5)
- Rosuvastatin Intermediates (CAS 937639-31-1)
- 2-Hydroxy Atorvastatin-d (CAS 265989-42-2)
- (S)-2-Amino-3-(5-mercapto-1-methyl-1H-imidazol-4-yl)propanoic acid (CAS 62982-24-5)
- 6-(5-Amino-5-carboxypentanamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (CAS 5286-29-3)
- 3-((1-Cyclopropyl-1h-tetrazol-5-yl)thio)propan-1-ol (CAS 1153278-96-6)
- tert-Butyl 3-bromo-6-methyl-1H-indole-1-carboxylate (CAS 914349-34-1)
- (2,6-Dichlorophenyl)methanesulfonyl chloride (CAS 85952-31-4)
- Fibrinopeptide A (human) (CAS 25422-31-5)
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