5-Bromo-7-(difluoromethyl)-1-methyl-1H-pyrazolo[4,3-b]pyridine CAS 1956366-44-1
| CAS No. | 1956366-44-1 |
| Molecular Formula | C8H6BrF2N3 |
| Molecular Weight | 262.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Bromo-7-(difluoromethyl)-1-methyl-1H-pyrazolo[4,3-b]pyridine (CAS 1956366-44-1), molecular formula C8H6BrF2N3 and molecular weight 262.05 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution, 5-Bromo-7-(difluoromethyl)-1-methyl-1H-pyrazolo[4,3-b]pyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 262.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Bromo-7-(difluoromethyl)-1-methyl-1H-pyrazolo[4,3-b]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrF2N3 |
| Molecular Weight | 262.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 3-(5-Bromo-2,3-difluorophenoxy)propanenitrile (CAS 1379356-55-4)
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- 4-Bromo-2-(2,2,2-trifluoroethoxy)-1,3-thiazole (CAS 1508037-30-6)
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Recommended Standards
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- 2-Amino-5-iodobenzamide, 97% (CAS 32658-67-6)
- 3-butylfuran-2-carboxylic acid (CAS 2024437-55-4)
- 6-Methoxy-N-(2-morpholinoethyl)quinolin-8-amine (CAS 94593-69-8)
- 1,2,3,5-Tetrafluoro-4-iodobenzene (CAS 13332-15-5)
- Ethyl 2-((5-fluoropyridin-2-yl)oxy)acetate (CAS 777-88-8)
- 3-(4-Iodophenoxymethyl)benzoic acid (CAS 693237-06-8)
- 7-Bromo-2-(3-oxobutyl)phthalazin-1(2H)-one (CAS 1437485-87-4)
- (3R)-3-(trifluoromethyl)pyrrolidin-3-ol (CAS 2090167-69-2)
- Trazodone Impurity 8 (CAS 6323-09-7)
- 4-Methyl-3-cyclohexen-1-one (contain up to 10% 4-methyl cyclohexanone) 4-Methyl-3-cyclohexenone 5259-65-4 (CAS 5259-65-4)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
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