Trazodone Impurity 8 CAS 6323-09-7
| CAS No. | 6323-09-7 |
| Molecular Formula | C23H30Cl2N4 |
| Molecular Weight | 433.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 433.42 g/mol gives Trazodone Impurity 8 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Trazodone Impurity 8 (CAS 6323-09-7), a pharmacopoeial impurity reference standard (molecular formula C23H30Cl2N4, MW 433.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Trazodone Impurity 8 (C23H30Cl2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 433.42 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Trazodone Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H30Cl2N4 |
| Molecular Weight | 433.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Trazodone Standards
- Trazodone Impurity 31 (CAS CATO-C4X-177231)
- Trazodone Impurity 106 (CAS CATO-C4X-1772106)
- Trazodone Impurity 92 (CAS CATO-C4X-177292)
- Trazodone EP Impurity D (CAS 1263358-13-9)
- Trazodone Hydrochloride EP Impurity J (CAS 1263358-12-8)
- Trazodone impurity 54 (CAS 55290-67-0)
- Trazodone impurity 53 (CAS 1346603-99-3)
- Trazodone Impurity 84 (CAS CATO-C4X-177284)
Recommended Standards
- Regadenoson Impurity 56 (CAS CATO-C4X-198556)
- Methyl 3-((tert-butoxycarbonyl)amino)-5-(2,2,2-trifluoro-1-((methylsulfonyl)oxy)ethyl)thiophene-2-carboxylate (CAS 2163771-83-1)
- H-Arg-Gly-Asp-Ser-OH (CAS 91037-65-9)
- 3,3'-(Isoindoline-1,3-diylidene)bis(quinoline-2,4(1H,3H)-dione) (CAS 85223-06-9)
- Pantoprazole Impurity 49 (CAS 1261238-06-5)
- Cefamandole EP Impurity C (CAS 36922-15-3)
- Rimegepant Impurity 142 (CAS CATO-C4X-2487142)
- Alatrofloxacin Mesylate (CAS 146961-77-5)
- N-Me-D-Tyr-OH (CAS 178357-84-1)
- (4E)-3-(Chloromethyl)-4-[(2-methyl-1H-indol-3-yl)-methylene]isoxazol-5(4H)-one 1142199-82-3 (CAS 1142199-82-3)
- tert-Butyl 1-(4-bromophenyl)cyclopropanecarboxylate (CAS 345965-53-9)
- Benzyl(2s)-2-(4-methoxycarbonylphenyl)-4-oxo-piperidine-1-carboxylate (CAS 2408761-20-4)
- (1-Chloroisoquinolin-7-yl)methanol (CAS 223671-64-5)
- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
Why CATO?
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