Pomalidomide Impurity 42 CAS 1957236-36-0
| CAS No. | 1957236-36-0 |
| Molecular Formula | C21H28N4O4 |
| Molecular Weight | 400.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Pomalidomide Impurity 42 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Pomalidomide Impurity 42 (CAS 1957236-36-0, C21H28N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Pomalidomide Impurity 42 (C21H28N4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Pomalidomide Impurity 42 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H28N4O4 |
| Molecular Weight | 400.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 4 |
Related Pomalidomide Standards
- Pomalidomide-5'-C6-acid (CAS 2412056-35-8)
- Pomalidomide-PEG2-propargyl (CAS 2138439-56-0)
- Pomalidomide 4'-PEG2-amine Pomalidomide - linker 1 4-[[2-[2-(2-Aminoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride 2245697-87-2 (CAS 2245697-87-2)
- Pomalidomide Impurity 40 (CAS 2093416-32-9)
- Pomalidomide-PEG3-OH (CAS 2140807-36-7)
- Pomalidomide-amido-C1-Br (CAS 2351106-38-0)
- Pomalidomide-C4-Br (CAS 2355289-79-9)
- Pomalidomide-5'-PEG1-C2-acid (CAS 2412056-43-8)
Recommended Standards
- Netupitant Impurity 38 (CAS CATO-C4X-122338)
- Tolvaptan Impurity 22 (CAS CATO-C4X-195522)
- Azilsartan Impurity 109 (CAS CATO-C4X-1096109)
- Vinorelbine Impurity 20 (CAS CATO-C4X-264220)
- Lisinopril Dihydrate EP Impurity G (CAS CATO-C4X-168132)
- Relebactam Impurity 142 (CAS CATO-C4X-2144142)
- Lenvatinib Impurity 72 (CAS CATO-C4X-114072)
- 5-(2-Ethoxy-4-methyl-phenoxymethyl)-4-methyl-4H-[1,2,4]triazole-3-thiol (CAS 708289-94-5)
- Methyl 2,6-Difluoro-4-methylbenzoate (CAS 79538-30-0)
- 9-methyl-2,3,4,9-tetrahydro-1H-carbazol-6-ol (CAS 13314-77-7)
- 4,5-Dimethoxybenzo[b]thiophene-2-carbohydrazide (CAS 1263206-36-5)
- Methyl 6-chloro-5-(hydroxymethyl)-3-methylpicolinate (CAS 1205671-73-3)
- (5-Fluoropyridin-2-yl)boronic Acid (CAS 946002-10-4)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com