Lisinopril Dihydrate EP Impurity G CAS CATO-C4X-168132
| CAS No. | CATO-C4X-168132 |
| Molecular Formula | C42H60N6O9 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Lisinopril Dihydrate EP Impurity G (C42H60N6O9HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Lisinopril Dihydrate EP Impurity G (CAS CATO-C4X-168132) is a certified pharmaceutical impurity reference standard with the molecular formula C42H60N6O9HCl and a molecular weight of 829.43 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C42H60N6O9 HCl |
| Molecular Weight | 829.43 g/mol |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Lisinopril Standards
- Lisinopril EP Impurity A (CAS 1012-05-1)
- Lisinopril Impurity N (CAS 103300-91-0)
- Lisinopril (8R,S)-Diketopiperazine (Mixture of Diastereomers) (CAS 1092813-99-4)
- Lisinopril Impurity 26 (CAS 112246-14-7)
- Lisinopril EP Impurity F (CAS 1132650-67-9)
- Lisinopril Impurity 15 (CAS 116169-90-5)
- Lisinopril Impurity 28 (CAS 1207346-27-7)
- Lisinopril EP Impurity G (CAS 1356839-89-8)
Recommended Standards
- Rizatriptan Impurity N8 (CAS 1034806-43-3)
- Aripiprazole Desethylene Impurity (CAS 1216394-63-6（free base）)
- Letermovir Impurity 26 (CAS CATO-CP155163)
- (R)-3-Fluoropyrrolidine (CAS 679431-51-7)
- 4-Ethylbenzo[d]oxazole-2-thiol (CAS 915151-24-5)
- 4-(Chloromethyl)-3-(2,6-difluorophenyl)-2,3-dihydro-1,3-thiazole-2-thione (CAS 866153-86-8)
- Isoquinolin-1-yl(p-tolyl)methanol (CAS 5467-96-9)
- 2-(4-Chlorophenyl)-4-phenyl-1H-imidazole (CAS 100558-20-1)
- 5-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline (CAS 100077-51-8)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com