Roxadustat Impurity 29 CAS 1959587-34-8
| CAS No. | 1959587-34-8 |
| Molecular Formula | C20H20N2O4 |
| Molecular Weight | 352.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Roxadustat Impurity 29 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Roxadustat Impurity 29 (CAS 1959587-34-8, C20H20N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C20H20N2O4, Roxadustat Impurity 29 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 352.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H20N2O4 |
| Molecular Weight | 352.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 2 |
Related Roxadustat Standards
- Roxadustat Impurity 156 (CAS CATO-C4X-2213156)
- Roxadustat (CAS 808118-40-3)
- Roxadustat Impurity 1 (CAS 2301113-15-3)
- Roxadustat Impurity 20 (CAS 2599284-48-5)
- Roxadustat Impurity 31 (CAS 808118-34-5)
- Roxadustat Impurity 94 (CAS CATO-C4X-221394)
- Roxadustat Impurity 172 (CAS CATO-C4X-2213172)
- Roxadustat Impurity 15 (CAS CATO-C4X-221315)
Recommended Standards
- Tegoprazan impurity 44 (CAS 1640981-11-8)
- Travoprost Impurity 57 (CAS CATO-C4X-192557)
- (-)-Corey lactone p-phenyl benzoate (CAS 31752-99-5)
- Travoprost Impurity 50 (CAS 2218532-68-2)
- Doxepin EP Impurity B (CAS 4504-88-5)
- Perindopril Impurity 34 (CAS CATO-C4X-125234)
- Bendamustine Impurity 18 (CAS CATO-C4X-127118)
- 1-(2-Hydroxyimidazo[2,1-a]isoquinolin-3-yl)ethanone (CAS 62472-00-8)
- 1,1'-(Phenazine-1,7-diyl)diethanone (CAS 62386-24-7)
- 1-(Sec-butylthio)-3-hydroxycyclobutane-1-carboxylic acid (CAS 1489270-47-4)
- 5-Methoxy-2H-benzo[b][1,4]thiazin-3(4H)-one (CAS 1245004-58-3)
- Thieno[3,2- d]pyrimidine (CAS 272-68-4)
- 2-(1h-Pyrazol-1-yl)pyridine-4-carboxylic acid (CAS 1152940-72-1)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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