2-(5-Chloro-2,3-dioxoindolin-1-yl)acetic acid CAS 19612-77-2
| CAS No. | 19612-77-2 |
| Molecular Formula | C10H6ClNO4 |
| Molecular Weight | 239.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(5-Chloro-2,3-dioxoindolin-1-yl)acetic acid (CAS 19612-77-2), a certified reference material (molecular formula C10H6ClNO4, MW 239.61 g/mol) for analytical method development and quality control.
2-(5-Chloro-2,3-dioxoindolin-1-yl)acetic acid (C10H6ClNO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(5-Chloro-2,3-dioxoindolin-1-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6ClNO4 |
| Molecular Weight | 239.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- 4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine (CAS 607368-87-6)
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- CAS 1062642-68-5 (CAS 1062642-68-5)
- (2-Pyridin-4-ylethyl)(tetrahydrofuran-2-ylmethyl)amine (CAS 373356-45-7)
- 3-(5-Bromo-2-chlorophenoxy)methylpyridine (CAS 1291487-23-4)
- Pyridin-1-ium 4-methylbenzenesulfonate (CAS 24057-28-1)
- 2-((4-Allyl-5-(((3,4-dichlorophenyl)amino)methyl)-4H-1,2,4-triazol-3-yl)thio)-N-isopropyl-N-phenylacetamide (CAS 540498-20-2)
- 6,7-Dihydro-5H-pyrazolo[5,1-b][1,3]oxazin-6-ol (CAS 1558277-46-5)
- [β-Asp]9-Semaglutide (CAS CATO-CPTD788605)
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