5-Chloro-7-(trifluoromethyl)thiazolo[5,4-d]pyrimidine CAS 1998-60-3
| CAS No. | 1998-60-3 |
| Molecular Formula | C6HClF3N3S |
| Molecular Weight | 239.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Chloro-7-(trifluoromethyl)thiazolo[5,4-d]pyrimidine (C6HClF3N3S) is characterized by a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 5-Chloro-7-(trifluoromethyl)thiazolo[5,4-d]pyrimidine (CAS 1998-60-3), a certified reference material (molecular formula C6HClF3N3S, MW 239.61 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Chloro-7-(trifluoromethyl)thiazolo[5,4-d]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6HClF3N3S |
| Molecular Weight | 239.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 7-Chloro-2-(trifluoromethyl)thiazolo[5,4-d]pyrimidine (CAS 1934497-36-5)
- 2-(5-Chloro-2,3-dioxoindolin-1-yl)acetic acid (CAS 19612-77-2)
- 4-Chloro-3-nitrobenzenesulfonyl fluoride (CAS 349-04-2)
- 5-Chloro-2-nitrobenzene-1-sulfonyl fluoride (CAS 1996-31-2)
- 7-Chloro-5-(trifluoromethyl)thiazolo[5,4-d]pyrimidine (CAS 1998-59-0)
- 1-(6-Chloro-4-nitro-1H-indazol-1-yl)ethanone (CAS 1010102-85-8)
- 1-(3-Chloro-4-methoxyphenyl)-2,2,2-trifluoroethan-1-amine (CAS 1039923-43-7)
- 5-(2-Chloro-5-nitrophenyl)-3-methyl-1,2,4-oxadiazole (CAS 1119395-85-5)
Recommended Standards
- 5-Fluoro-2-nitrobenzenesulfonyl Chloride (CAS 82711-97-5)
- 4-Fluoro-3-nitrobenzenesulfonyl Chloride (CAS 6668-56-0)
- 4-Fluoro-2-nitrobenzenesulfonyl chloride (CAS 568586-10-7)
- 3-Fluoro-4-nitrobenzenesulfonyl Chloride (CAS 86156-93-6)
- 2-Chloro-7-ethoxy-1,8-naphthyridine (CAS 15944-32-8)
- N-Desmethyl citalopram Oxalate D4 (CAS 62498-68-4(un))
- 4-(3-Hydroxyphenyl)-2-butanone (CAS 56363-73-6)
- 1-[(3,4-Difluorophenyl)methyl]-2-methylpiperazine (CAS 1240581-16-1)
- N-(37-(4-Aminobutyl)-36,39-dioxo-2,5,8,11,14,17,20,23,26,29,32-undecaoxa-35,38-diazatetracontan-40-yl)octadec-9-enamide (CAS 2353409-68-2)
- N-allyl-2-(1-(2,4-dichlorobenzyl)-6-oxo-1,6-dihydropyridine-3-carbonyl)hydrazine-1-carbothioamide (CAS 477853-04-6)
- 2-Chloro-N-(cyclopropylmethyl)-6-methylaniline (CAS 1531156-27-0)
- tert-Butyl 1-methyl-2-oxo-3-azepanylcarbamate (CAS 1424939-98-9)
- 4-Amino-2-(difluoromethyl)-6-(trifluoromethyl)pyridin-3-ol (CAS 1805216-20-9)
- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com