1-(2-Hydroxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one CAS 19685-20-2
| CAS No. | 19685-20-2 |
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(2-Hydroxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one (C10H10N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 1-(2-Hydroxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one (CAS 19685-20-2), a certified reference material (molecular formula C10H10N2O2, MW 190.20 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 2 |
Related Hydroxyphenyl Standards
- Ethyl 3-(4-hydroxyphenyl)propiolate (CAS 1030828-84-2)
- Ethyl 3-(3-hydroxyphenyl)prop-2-ynoate (CAS 1294453-44-3)
- 2-(4-Hydroxyphenyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one (CAS 780806-23-7)
- 2-(4-Hydroxyphenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one (CAS 76858-78-1)
- 1-(4-Hydroxyphenyl)pyrrolidine-2,5-dione (CAS 10187-21-0)
- 1-(3-Hydroxyphenyl)pyrrolidine-2,5-dione (CAS 1204-36-0)
- 1-(2-Hydroxyphenyl)pyrrolidine-2,5-dione (CAS 79252-84-9)
- 2-(2-Hydroxyphenyl)-4-methyloxazol-5(4H)-one (CAS 56145-96-1)
Recommended Standards
- Methyl 1-methyl-1H-pyrrolo[3,2-b]pyridine-5-carboxylate (CAS 1956370-67-4)
- 2-(1H-1,3-Benzodiazol-2-yl)acetohydrazide (CAS 19731-02-3)
- 3-Benzyloxolane-2,5-dione (CAS 19544-43-5)
- (1H-Benzo[d]imidazol-2-yl)methyl acetate (CAS 33809-91-5)
- Sodium Tetrapropylborate (CAS 105146-61-0)
- 4-Cyclohexyl-5-(4-nitrophenyl)-4H-1,2,4-triazole-3-thiol (CAS 17050-54-3)
- 2,5-Dichloro-3-(difluoromethoxy)benzyl chloride (CAS 1807184-86-6)
- n-(2-Fluoro-4-methylphenyl)tetrahydro-2h-pyran-4-amine (CAS 1157009-65-8)
- 2-(1H-Pyrrol-1-yl)benzothioamide (CAS 175277-82-4)
- 3,4-dimethylpyrrolidin-2-one (CAS 39585-10-9)
- Methyl 2-fluoro-4-iodo-5-nitrobenzoate (CAS 1807741-24-7)
- 2-tert-Butyl 5-methyl 7-oxa-2-azaspiro[3.5]nonane-2,5-dicarboxylate (CAS 1445950-84-4)
- Furo[3,2-b]benzofuran (CAS 247-40-5)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
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