1-Chloro-2-ethenyl-3-fluorobenzene CAS 196862-01-8
| CAS No. | 196862-01-8 |
| Molecular Formula | C8H6ClF |
| Molecular Weight | 156.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Chloro-2-ethenyl-3-fluorobenzene (CAS 196862-01-8), molecular formula C8H6ClF and molecular weight 156.58 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Chloro-2-ethenyl-3-fluorobenzene (C8H6ClF) is characterized by fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Chloro-2-ethenyl-3-fluorobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF |
| Molecular Weight | 156.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-1-fluoro-4-vinylbenzene (CAS 1011029-41-6)
- 1-Chloro-4-(1-fluorovinyl)benzene (CAS 106263-12-1)
- 4-Chloro-3-fluorostyrene (CAS 1263414-46-5)
- 2-Chloro-1-fluoro-3-vinylbenzene (CAS 1263414-46-7)
- 4-Chloro-2-fluorostyrene (CAS 711017-44-6)
- 2-Chloro-6-methylcyclohexa-2,5-diene-1,4-dione (CAS 1123-64-4)
- 3-Chloro-5-methylpyrazine-2-carbaldehyde (CAS 1197235-63-4)
- 2-Chloro-5,7-dihydrofuro[3,4-d]pyrimidine (CAS 1233932-44-9)
Recommended Standards
- Oxetane-3-sulfonyl chloride (CAS 1393585-06-2)
- 2-(Methylsulfonyl)acetyl chloride (CAS 56841-99-7)
- 2-Oxopropane-1-sulfonyl chloride (CAS 637031-08-4)
- Indometacin EP Impurity A (CAS 74-11-3)
- 3-Bromo-7-chloro-4-(piperazin-1-yl)quinoline (CAS 927801-09-0)
- 2-Chloro-3-((3,4-dichlorobenzyl)amino)naphthalene-1,4-dione (CAS 866157-71-3)
- Theaflavin 3,3’-Digallate (CAS 30462-35-2)
- (3-Bromo-5,6,7,8-tetrahydroquinolin-5-yl)methanamine (CAS 2387602-08-4)
- 5-(4-Ethoxyphenyl)-1H-pyrazol-3-amine (CAS 129117-13-1)
- 5,7-Difluoro-1H-indole-2-carbaldehyde (CAS 943026-51-5)
- THIOFANOX (CAS 39196-18-4)
- (S)-tert-Butyl 1-cyclohexylpyrrolidin-3-ylcarbamate (CAS 178688-10-3)
- Revefenacin impurity 95 (CAS CATO-C4X-203195)
- [γ-Glu]15 Semaglutide (CAS CATO-C4X-222690)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com