rac-2,2,2-trifluoro-N-[(3R,4S)-4-(3-fluoro-4-methoxyphenyl)piperidin-3-yl]acetamide CAS 1969288-07-0
| CAS No. | 1969288-07-0 |
| Molecular Formula | C14H16F4N2O2 |
| Molecular Weight | 320.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, rac-2,2,2-trifluoro-N-[(3R,4S)-4-(3-fluoro-4-methoxyphenyl)piperidin-3-yl]acetamide (C14H16F4N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 320.28 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
rac-2,2,2-trifluoro-N-[(3R,4S)-4-(3-fluoro-4-methoxyphenyl)piperidin-3-yl]acetamide (CAS 1969288-07-0), molecular formula C14H16F4N2O2 and molecular weight 320.28 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H16F4N2O2 |
| Molecular Weight | 320.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related rac Standards
- 2,2,2-Trifluoro-N-(4-(3-fluoro-4-methoxyphenyl)piperidin-3-yl)acetamide (CAS 1432680-28-8)
- (2E)-4,4,4-trifluoro-1-phenyl-2-(phenylhydrazono)butane-1,3-dione (CAS 76073-64-8)
- 1,1,1-trifluoro-3-({[4-methyl-6-(methylthio)-1,3,5-triazin-2-yl]amino}methylidene)pentane-2,4-dione (CAS 649665-96-3)
- Trifluoro-methanesulfonic acid dimethyloctylsilyl ester (CAS 136445-80-2)
- Trifluoro-methanesulfonic acid (1,1-dimethylethyl)bis(1-methylethyl)silyl ester (CAS 561322-37-0)
- 2,2,2-Trifluoro-1-{1-[tris(propan-2-yl)silyl]-1h-pyrrol-3-yl}ethan-1-one (CAS 130408-88-7)
- Methyl 4,4,4-trifluoro-2-formamido-3-hydroxy-3-(4-methoxyphenyl)butanoate (CAS 649573-18-2)
- 1,1,1-Trifluoro-3-(piperidin-1-yl)propan-2-yl 3-fluorobenzoate (CAS 477848-33-2)
Recommended Standards
- Ethyl 2-(diphenoxyphosphoryl)acetate (CAS 16139-79-0)
- 2-(Bis(benzyloxy)phosphoryl)acetic acid (CAS 53243-58-6)
- (2R,3S,4S,5R)-4-Fluoro-2-(6-(furan-2-yl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 1612191-89-5)
- 2-[(3,4-Dichlorophenyl)sulfanyl]-N,N-bis(propan-2-yl)acetamide (CAS 339097-68-6)
- 2-Fluoro-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acrylamide (CAS 2901130-88-7)
- 6-Methoxy-3-(prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-imine hydrobromide (CAS 127346-14-9)
- 5-Ethyloctahydro-5,8-methanoindolizine (CAS 90307-73-6)
- 2-tert-Butyl 4-methyl 2-azabicyclo[2.1.1]hexane-2,4-dicarboxylate (CAS 2306425-69-2)
- 2-(1-Aminoethyl)thiazole-4-carboxamide (CAS 1541856-68-1)
- Methyl 3,3-dimethyl-2-oxocycloheptane-1-carboxylate (CAS 1190305-65-7)
- Methyl 2-(3-bromo-6-chloro-2-pyridyl)acetate (CAS 1211581-13-3)
- methyl 3-amino-3-(pyridin-3-yl)butanoate (CAS 1508381-33-6)
- 5-Methyl-6-oxo-1-phenyl-1,4,5,6-tetrahydro-1,2,4-triazine-3-carboxylic acid (CAS 1214640-04-6)
- Insulin degludec (CAS 844439-96-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com