2-Iodo-3-nitrophenol CAS 197243-48-4
| CAS No. | 197243-48-4 |
| Molecular Formula | C6H4INO3 |
| Molecular Weight | 265.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Iodo-3-nitrophenol.
CATO supplies 2-Iodo-3-nitrophenol (CAS 197243-48-4), a certified reference material (molecular formula C6H4INO3, MW 265.01 g/mol) for analytical method development and quality control.
The molecular framework of 2-Iodo-3-nitrophenol (C6H4INO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Iodo-3-nitrophenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4INO3 |
| Molecular Weight | 265.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 4-Iodo-3-nitrophenol (CAS 113305-56-9)
- 2-Iodo-6-nitrophenol (CAS 13073-26-2)
- 3-Iodo-5-nitropyridin-4-amine (CAS 1352905-69-1)
- 5-Iodo-4-oxo-1,4-dihydropyridine-3-carboxylic acid (CAS 1698365-45-5)
- 2-Iodo-5-nitrophenol (CAS 197243-46-2)
- 3-Iodo-2-nitrophenol (CAS 861010-57-3)
- 3-Iodo-4-nitrophenol (CAS 50590-07-3)
- 3-Iodo-5-nitrophenol (CAS 861338-13-8)
Recommended Standards
- 2-Amino-5-iodo-3-nitropyridine (CAS 25391-57-5)
- 1,3-Dichloro-5-(perfluoroethyl)benzene (CAS 1955524-45-4)
- 2-Chloro-3,5-dinitrobenzoyl chloride (CAS 42747-54-6)
- 2-Hydroxy-5-iodonicotinic Acid (CAS 390360-97-1)
- Tofacitinib RS/SR mixture Citrate (CAS CATO-C4X-107929)
- 2-Chloro-N,N-dimethyl-5-sulfamoylbenzamide (CAS 1099011-81-0)
- 1-(2-(Difluoromethoxy)-4-fluorophenyl)ethan-1-amine (CAS 1341918-44-2)
- 4-Cyano-4-iodobenzophenone (CAS 890098-67-6)
- Zinc(II) Trifluoromethanesulfonate (CAS 54010-75-2)
- 2-Chloro-6-(dibromomethyl)-3-fluorobenzonitrile (CAS 1134335-07-1)
- 1-(P-tolyl)cyclohexan-1-amine hydrochloride (CAS 125802-03-1)
- METHYL 3-AMINO-5-METHOXYBENZOATE (CAS 217314-47-1)
- 4-Bromo-5-(difluoromethyl)-2-fluoropyridine-3-sulfonamide (CAS 1805370-33-5)
- Semaglutide Impurity 145 (CAS CATO-C4X-2226145)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com