2-Iodo-5-nitrophenol CAS 197243-46-2
| CAS No. | 197243-46-2 |
| Molecular Formula | C6H4INO3 |
| Molecular Weight | 265.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Iodo-5-nitrophenol (C6H4INO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-Iodo-5-nitrophenol (CAS 197243-46-2), molecular formula C6H4INO3 and molecular weight 265.01 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4INO3 |
| Molecular Weight | 265.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 4-Iodo-3-nitrophenol (CAS 113305-56-9)
- 2-Iodo-6-nitrophenol (CAS 13073-26-2)
- 3-Iodo-5-nitropyridin-4-amine (CAS 1352905-69-1)
- 5-Iodo-4-oxo-1,4-dihydropyridine-3-carboxylic acid (CAS 1698365-45-5)
- 2-Iodo-3-nitrophenol (CAS 197243-48-4)
- 3-Iodo-2-nitrophenol (CAS 861010-57-3)
- 3-Iodo-4-nitrophenol (CAS 50590-07-3)
- 3-Iodo-5-nitrophenol (CAS 861338-13-8)
Recommended Standards
- 1,3-Dichloro-5-(perfluoroethyl)benzene (CAS 1955524-45-4)
- 2-Amino-5-iodo-3-nitropyridine (CAS 25391-57-5)
- 6-Hydroxy-4-iodopicolinic acid (CAS 1393572-07-0)
- 2-Chloro-3,5-dinitrobenzoyl chloride (CAS 42747-54-6)
- (2S)-2-(fluoromethyl)piperidine hydrochloride (CAS 886216-73-5)
- 1-(2-Bromoethoxy)-2-chloro-4-methylbenzene (CAS 796098-78-7)
- 6-Amino-2-(benzylamino)pyrimidin-4(3H)-one (CAS 104296-01-7)
- 4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid (CAS 1236196-77-2)
- N-propylazetidine-1-carboxamide (CAS 164735-74-4)
- di-tert-butylChlorophosphate (CAS 56119-60-9)
- Benzyl 2-ethynyl-2-methylpyrrolidine-1-carboxylate (CAS 2169137-09-9)
- Roxadustat Impurity 37 (CAS CATO-C4X-221337)
- Bromhexine EP Impurity E (CAS 1660957-93-6)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
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