1-(2-Hydroxyphenyl)pyrrolidin-2-one CAS 19734-02-2

Purity 97%+In StockPharmaceutical Standards
CAS No.19734-02-2
Molecular FormulaC10H11NO2
Molecular Weight177.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2-Hydroxyphenyl)pyrrolidin-2-one CAS 19734-02-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 177.20 g/mol gives 1-(2-Hydroxyphenyl)pyrrolidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 1-(2-Hydroxyphenyl)pyrrolidin-2-one (CAS 19734-02-2), a certified reference material (molecular formula C10H11NO2, MW 177.20 g/mol) for analytical method development and quality control.

The molecular framework of 1-(2-Hydroxyphenyl)pyrrolidin-2-one (C10H11NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H11NO2
Molecular Weight177.20 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Nitrogen Atoms1

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