Drospirenone 5β-Hydroxy Impurity CAS 197721-70-3
| CAS No. | 197721-70-3 |
| Molecular Formula | C24H32O4 |
| Molecular Weight | 384.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Drospirenone 5β-Hydroxy Impurity (C24H32O4) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 384.51 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Drospirenone 5β-Hydroxy Impurity (CAS 197721-70-3), a pharmacopoeial impurity reference standard (molecular formula C24H32O4, MW 384.51 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H32O4 |
| Molecular Weight | 384.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
Related Drospirenone Standards
- Drospirenone AcidDISCONTINUED, offer stable alternates (CAS 776251-13-9)
- Drospirenone EP Impurity B (CAS CATO-C4X-16242)
- Drospirenone 5,5-Diol (CAS 863329-70-8)
- Drospirenone Impurity 17 (CAS 82543-17-7)
- Drospirenone 3,5,5-Triol (CAS 1079392-41-8)
- Drospirenone Impurity 13(Mixture of Diastereomers) (CAS CATO-C4X-162413)
- Drospirenone Impurity 12 (CAS 82543-18-8)
- Drospirenone-20,20,21,21-d4 (CAS 2376035-94-6)
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Why CATO?
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