Drospirenone Impurity 12 CAS 82543-18-8
| CAS No. | 82543-18-8 |
| Molecular Formula | C24H38O4 |
| Molecular Weight | 390.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Drospirenone Impurity 12 is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Drospirenone Impurity 12 (CAS 82543-18-8), a pharmacopoeial impurity reference standard (molecular formula C24H38O4, MW 390.56 g/mol) used for the identification and quantification of trace impurities in APIs.
Drospirenone Impurity 12 (C24H38O4) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Drospirenone Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H38O4 |
| Molecular Weight | 390.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
Related Drospirenone Standards
- Drospirenone 3,5,5-Triol (CAS 1079392-41-8)
- Drospirenone Impurity 13(Mixture of Diastereomers) (CAS CATO-C4X-162413)
- Drospirenone 5,5-Diol (CAS 863329-70-8)
- Drospirenone Impurity 17 (CAS 82543-17-7)
- Drospirenone AcidDISCONTINUED, offer stable alternates (CAS 776251-13-9)
- Drospirenone EP Impurity B (CAS CATO-C4X-16242)
- Drospirenone 5β-Hydroxy Impurity (CAS 197721-70-3)
- Drospirenone EP Impurity G (CAS 932388-90-4)
Recommended Standards
- Ursodeoxycholic Acid impurity 96 (CAS CATO-C4X-142296)
- Finasteride Impurity 37 (CAS CATO-C4X-164537)
- Ursodeoxycholic Acid impurity 95 (CAS CATO-C4X-142295)
- Finasteride Impurity 51 (CAS CATO-C4X-164551)
- Dapagliflozin impurity 182 (CAS CATO-C4X-1138182)
- Azilsartan Impurity 174 (CAS 2382294-55-3)
- Ethacridine Lactate Impurity 11 (CAS CATO-C4X-260911)
- 3-(2-Methoxyphenyl)-1,1-dimethylurea (CAS 20575-80-8)
- 1-Chloro-4-(1,1,2,2-tetrafluoroethoxy)benzene (CAS 75820-58-5)
- 6-Amino-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid (CAS 1260386-70-6)
- Carbocisteine impurity 53 (CAS CATO-C4X-201053)
- 1-Methyl-5-propoxy-6,7,8,9-tetrahydroisoxazolo[5,4-c]isoquinoline (CAS 88786-38-3)
- 5-(2-Hydroxyethyl)-4-imino-1-methyl-4,5-dihydro-1H-imidazo[4,5-c]pyridin-2(3H)-one (CAS 777813-86-2)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com