1-(2-Methyl-6-(trifluoromethyl)pyridin-3-yl)-3-(3-(pyrrolidin-1-yl)phenyl)urea CAS 1980064-08-1
| CAS No. | 1980064-08-1 |
| Molecular Formula | C18H19F3N4O |
| Molecular Weight | 364.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(2-Methyl-6-(trifluoromethyl)pyridin-3-yl)-3-(3-(pyrrolidin-1-yl)phenyl)urea is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(2-Methyl-6-(trifluoromethyl)pyridin-3-yl)-3-(3-(pyrrolidin-1-yl)phenyl)urea (CAS 1980064-08-1) is a high-purity analytical reference standard with the molecular formula C18H19F3N4O and a molecular weight of 364.36 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(2-Methyl-6-(trifluoromethyl)pyridin-3-yl)-3-(3-(pyrrolidin-1-yl)phenyl)urea is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 364.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19F3N4O |
| Molecular Weight | 364.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Methyl Standards
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Recommended Standards
- 1-(4-Phenylpiperazin-1-yl)-2-(3-(trifluoromethyl)phenoxy)ethan-1-one (CAS 866153-13-1)
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- 1-(6-Methyl-2-pyridinyl)-N-[(Z)-1-(4-nitrophenyl)ethylidene]-1H-imidazole-4-carbohydrazide (CAS 477858-69-8)
- tert-Butyl(3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)dimethylsilane (CAS 1562341-00-7)
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- 2-(4-Chlorophenyl)-5,7-dihydroxy-4H-chromen-4-one (CAS 152969-69-2)
- (2-(2-Methoxyphenyl)cyclopropyl)methanol (CAS 1315375-65-5)
- Methyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate (CAS 75092-26-1)
- [(2S,3R,4S,5S,6S)-3,4,5-trihydroxy-6-[(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]methyl dihydrogen phosphate (CAS 4484-88-2)
- 1-(Tert-butyl) 3-ethyl 3-phenylpiperidine-1,3-dicarboxylate fumarate (CAS 1980007-98-4)
- [Tyr15] Fibrinopeptide B, human (CAS 125455-56-3)
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