3-Phenyl-2-(2-(trifluoromethyl)benzyl)-1H-inden-1-one CAS 337921-67-2
| CAS No. | 337921-67-2 |
| Molecular Formula | C23H15F3O |
| Molecular Weight | 364.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Phenyl-2-(2-(trifluoromethyl)benzyl)-1H-inden-1-one (CAS 337921-67-2), molecular formula C23H15F3O and molecular weight 364.36 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, a hydroxyl group, an ether linkage, fluorine substitution, 3-Phenyl-2-(2-(trifluoromethyl)benzyl)-1H-inden-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 364.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H15F3O |
| Molecular Weight | 364.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Phenyl Standards
- 1-(2-(Trifluoromethyl)phenyl)-3-(2,2,4-trimethyl-2,3-dihydrobenzofuran-7-yl)urea (CAS 866150-32-5)
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- 3'-(3-(Trifluoromethyl)phenyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 79962-59-7)
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- 6'-[3-(Trifluoromethyl)phenyl]-2,4-dihydrospiro[1-benzopyran-3,3'-[1,5]dioxane]-4-one (CAS 339029-02-6)
Recommended Standards
- 3-(1,3-Dioxan-2-yl)-1-(4'-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)propan-1-one (CAS 898757-56-7)
- 4-(4-((tert-Butoxycarbonyl)amino)-1-methyl-1H-imidazole-2-carboxamido)-1-methyl-1H-imidazole-2-carboxylic acid (CAS 502170-49-2)
- 2-{[(3-fluorophenyl)methyl]sulfanyl}-5-[3-(trifluoromethyl)phenyl]pyrimidine (CAS 866136-19-8)
- 4-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole (CAS 2803476-12-0)
- 6-(Propan-2-yloxy)-1h-indole-2-carboxylic acid (CAS 881041-46-9)
- 3-({6-ethylthieno[2,3-d]pyrimidin-4-yl}amino)propanoic acid (CAS 690702-08-0)
- 2,3-Bis(4-fluorophenyl)propanoic acid (CAS 1017324-10-5)
- 5-Bromo-N1-isobutylbenzene-1,2-diamine (CAS 939054-44-1)
- 5-Hydrazineyl-1-methyl-3-(trifluoromethyl)-1H-pyrazole hydrochloride (CAS 1855888-52-6)
- 2-Eicosyl-1-tetracosanol (CAS 73761-81-6)
- (3-Chloro-4-hydroxyphenyl)boronic acid (CAS 182344-13-4)
- (E)-3-[4-(3-Formyl-1H-indol-1-yl)phenyl]-2-(2-thienyl)-2-propenenitrile (CAS 692287-44-8)
- (R)-1-((R)-1-(4-Methoxyphenyl)ethyl)-5-oxopyrrolidine-3-carbaldehyde (CAS 1650544-38-9)
- Smac-N7 Peptide (CAS 401913-57-3)
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