4-Bromo-5-(methylamino)-2-(2-oxopropyl)pyridazin-3(2H)-one CAS 198023-95-9

Purity 97%+In StockPharmaceutical Standards
CAS No.198023-95-9
Molecular FormulaC8H10BrN3O2
Molecular Weight260.09 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Bromo-5-(methylamino)-2-(2-oxopropyl)pyridazin-3(2H)-one CAS 198023-95-9 chemical structure

Description

4-Bromo-5-(methylamino)-2-(2-oxopropyl)pyridazin-3(2H)-one (CAS 198023-95-9), molecular formula C8H10BrN3O2 and molecular weight 260.09 g/mol, is a CATO reference standard with documented purity and traceability.

4-Bromo-5-(methylamino)-2-(2-oxopropyl)pyridazin-3(2H)-one (C8H10BrN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H10BrN3O2
Molecular Weight260.09 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2013
Halogen ContentBr-containing
Nitrogen Atoms3

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