Methyl 2,3-difluoro-4-formylbenzoate CAS 1989657-57-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 2,3-difluoro-4-formylbenzoate.

Methyl 2,3-difluoro-4-formylbenzoate (CAS 1989657-57-9) is a high-purity analytical reference standard with the molecular formula C9H6F2O3 and a molecular weight of 200.14 g/mol.

Methyl 2,3-difluoro-4-formylbenzoate (C9H6F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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