7-fluoro-1,2,3,4-tetrahydroisoquinoline-8-carboxylic acid hydrochloride CAS 1989671-78-4
| CAS No. | 1989671-78-4 |
| Molecular Formula | C10H10FNO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 231.65 g/mol gives 7-fluoro-1,2,3,4-tetrahydroisoquinoline-8-carboxylic acid hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
7-fluoro-1,2,3,4-tetrahydroisoquinoline-8-carboxylic acid hydrochloride (CAS 1989671-78-4) is a high-purity analytical reference standard with the molecular formula C10H10FNO2HCl and a molecular weight of 231.65 g/mol.
The molecular framework of 7-fluoro-1,2,3,4-tetrahydroisoquinoline-8-carboxylic acid hydrochloride (C10H10FNO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-fluoro-1,2,3,4-tetrahydroisoquinoline-8-carboxylic acid hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10FNO2 HCl |
| Molecular Weight | 231.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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