5-Chlorothiophene-3-boronic acid CAS 199659-23-9
| CAS No. | 199659-23-9 |
| Molecular Formula | C4H4BClO2S |
| Molecular Weight | 162.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chlorothiophene-3-boronic acid is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chlorothiophene-3-boronic acid (CAS 199659-23-9), a certified reference material (molecular formula C4H4BClO2S, MW 162.40 g/mol) for analytical method development and quality control.
5-Chlorothiophene-3-boronic acid (C4H4BClO2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H4BClO2S |
| Molecular Weight | 162.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.5 |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chlorothiophene Standards
- 4-Chlorothiophene-2-boronic acid (CAS 1133931-02-8)
- 4-Chlorothiophene-3-carboxamide (CAS 1174537-09-7)
- 3-Chlorothiophene-2-carboxamide (CAS 147123-68-0)
- 4-Chlorothiophene-2-carboxamide (CAS 176203-88-6)
- 5-Chlorothiophene-3-carboxamide (CAS 189330-09-4)
- 2-Chlorothiophene-3-carboxamide (CAS 189330-14-1)
- 4-Chlorothiophene-2-carboximidamide (CAS 1361003-73-7)
- 2-Acetyl-3-chlorothiophene (CAS 89581-82-8)
Recommended Standards
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