1-(2-Fluorophenyl)-5-oxo-3-pyrrolidinecarboxylic acid CAS 1998-86-3
| CAS No. | 1998-86-3 |
| Molecular Formula | C11H10FNO3 |
| Molecular Weight | 223.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Fluorophenyl)-5-oxo-3-pyrrolidinecarboxylic acid.
1-(2-Fluorophenyl)-5-oxo-3-pyrrolidinecarboxylic acid (CAS 1998-86-3) is a high-purity analytical reference standard with the molecular formula C11H10FNO3 and a molecular weight of 223.20 g/mol.
1-(2-Fluorophenyl)-5-oxo-3-pyrrolidinecarboxylic acid (C11H10FNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(2-Fluorophenyl)-5-oxo-3-pyrrolidinecarboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10FNO3 |
| Molecular Weight | 223.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 1-(3-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid (CAS 1017473-77-6)
- Methyl 3-(4-fluorophenyl)-2-isocyanatopropionate (CAS 1211371-51-5)
- 3-(3-Fluorophenyl)-5-oxoproline (CAS 1219160-89-0)
- 3-(4-Fluorophenyl)-5-oxoproline (CAS 1219340-97-2)
- 3-(3-Fluorophenyl)-5-methyl-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 1326815-03-5)
- (1-(4-Fluorophenyl)-1H-1,2,3-triazole-4,5-diyl)dimethanol (CAS 728024-47-3)
- (E)-(3-(3-fluorophenyl)acryloyl)glycine (CAS 853355-85-8)
- 1-(2-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid (CAS 618070-32-9)
Recommended Standards
- 1-(3-amino-4-fluoro-phenyl)hexahydropyrimidine-2,4-dione (CAS 2703772-51-2)
- 1-(2-Fluorobenzoyl)azetidine-3-carboxylic acid (CAS 866150-19-8)
- 1-(3-Fluorophenyl)-5-oxopyrrolidine-3-carboxylic Acid (CAS 566154-63-0)
- (E)-4-((4-Fluorobenzyl)amino)-4-oxobut-2-enoic acid (CAS 863647-67-0)
- (3-Bromo-6-chloro-2-fluorophenyl)(4-methylpiperazin-1-yl)methanone (CAS 2504202-64-4)
- tert-Butyl 3-((4-methylpyrimidin-2-yl)amino)pyrrolidine-1-carboxylate (CAS 1261232-92-1)
- Sofalcone (CAS 64506-49-6)
- 1-(Bromomethyl)-2,3-difluoro-5-methoxy-4-methylbenzene (CAS 1706430-78-5)
- 5-Bromo-2-(furan-2-ylmethylamino)pyrimidine (CAS 886366-01-4)
- Biotin Impurity 36 (CAS 1535184-53-2)
- (5-(3-(Trifluoromethyl)phenyl)pyridin-3-yl)methanamine (CAS 1356111-01-7)
- 4-(M-tolyl)butane-2-sulfonamide (CAS 1248987-67-8)
- tert-Butyl 3-(methoxymethyl)pyrrolidine-1-carboxylate (CAS 146257-05-8)
- Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 90880-35-6)
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