Biotin Impurity 36 CAS 1535184-53-2
| CAS No. | 1535184-53-2 |
| Molecular Formula | C15H22N4O4S |
| Molecular Weight | 354.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Biotin Impurity 36 (C15H22N4O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Biotin Impurity 36 (CAS 1535184-53-2), a pharmacopoeial impurity reference standard (molecular formula C15H22N4O4S, MW 354.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H22N4O4S |
| Molecular Weight | 354.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Biotin Standards
- Biotin Impurity 04 (CAS 26339-40-2)
- Biotin-PEG1-azide (CAS 1204085-48-2)
- D-(+)Biotin 2-Nitrophenyl Ester (CAS 131303-71-4)
- Biotin-C2-maleimide (CAS 139554-72-6)
- Biotin Impurity N1 (CAS 28092-52-6)
- Biotin impurity 23 (CAS 33607-57-7)
- Biotin-PEG2-C1-aldehyde (CAS 2408505-11-1)
- Biotin Impurity 4 (CAS 76335-62-1)
Recommended Standards
- Pioglitazone Impurity 6 (CAS 144809-28-9)
- Meloxicam-d3 (CAS 942047-63-4)
- Pioglitazone impurity 38 (CAS CATO-C4X-138338)
- Brinzolamide Impurity 17 (CAS 154127-41-0)
- Labetalol Impurity 68 (CAS CATO-C4X-246668)
- Landiolol Impurity 45 (CAS CATO-C4X-262145)
- Topiroxostat impurity 72 (CAS CATO-C4X-105572)
- 1-(2-Bromo-1,1,2,2-tetrafluoroethoxy)-4-fluorobenzene (CAS 2032375-46-3)
- (E)-N-(1-(4-Bromo-2-hydroxyphenyl)ethylidene)-2-methylpropane-2-sulfinamide (CAS 2890778-14-8)
- 1-(Tert-butoxycarbonyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1782397-42-5)
- 5-Chloroquinoxaline-2-carbonitrile (CAS 1231761-46-8)
- Ethyl 1-(2-hydroxyethyl)-2-methyl-1H-benzo[d]imidazole-5-carboxylate (CAS 299927-12-1)
- 2-(1-Naphthyl)propionaldehyde (CAS 52417-52-4)
- Fibrinopeptide A (human) (CAS 25422-31-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com