Isavuconazole Impurity 2 CAS 2001051-99-4
| CAS No. | 2001051-99-4 |
| Molecular Formula | C13H12F2N4O |
| Molecular Weight | 278.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Isavuconazole Impurity 2 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 278.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Isavuconazole Impurity 2 (CAS 2001051-99-4), a pharmacopoeial impurity reference standard (molecular formula C13H12F2N4O, MW 278.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12F2N4O |
| Molecular Weight | 278.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Isavuconazole Standards
- Isavuconazole Impurity 1 (CAS 2069200-13-9)
- Isavuconazole Impurity 108 (CAS CATO-C4X-1236108)
- Isavuconazole Impurity 158 (CAS CATO-C4X-1236158)
- Isavuconazole Impurity 34 (CAS 2001052-01-1)
- Isavuconazole Related Compoun 1 (CAS 241479-74-3)
- Isavuconazole Impurity 79 (CAS 483340-20-1)
- Isavuconazole Impurity 7 (CAS 2733698-17-2)
- Isavuconazole Impurity 223 (CAS CATO-C4X-1236223)
Recommended Standards
- Allopurinol Impurity 32 (CAS 52632-17-4)
- Allopurinol Impurity 7 (CAS 321571-07-7)
- Potassium Clavulanate EP Impurity F (CAS 1260857-16-6)
- Lenalidomide Impurity 3 (CAS 295357-66-3)
- Cholic Acid Impurity 84 (CAS CATO-C4X-116084)
- Cilastatin Impurity 19 (CAS CATO-C4X-196019)
- Rivaroxaban Impurity 25 (CAS CATO-C4X-109025)
- 1-ethylsulfonylpiperidin-3-one (CAS 1536213-21-4)
- Avanafil Impurity 103 (CAS CATO-C4X-1118103)
- n-(4-Fluoro-2-iodophenyl)pyrrolidine-2-carboxamide (CAS 1394631-06-1)
- 1-(3,5-Dimethylphenyl)propan-2-one (CAS 75251-27-3)
- 3-(Cyclohexylmethyl)-5-methoxyphenol (CAS 1243395-46-1)
- 3-(2-Bromo-4-chloro-3,5-dimethylphenoxy)-piperidine hydrochloride (CAS 1220020-78-9)
- Tyr-Proinsulin C-Peptide (55-89) (human) (CAS 139532-11-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com