Lenalidomide Impurity 3 CAS 295357-66-3
| CAS No. | 295357-66-3 |
| Molecular Formula | C13H14N2O5 |
| Molecular Weight | 278.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Lenalidomide Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Lenalidomide Impurity 3 (CAS 295357-66-3) is a certified pharmaceutical impurity reference standard with the molecular formula C13H14N2O5 and a molecular weight of 278.26 g/mol.
The molecular framework of Lenalidomide Impurity 3 (C13H14N2O5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H14N2O5 |
| Molecular Weight | 278.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Lenalidomide Standards
- Lenalidomide Impurity 1 (CAS 2197414-57-4)
- Lenalidomide Impurity 2 (CAS 2197420-75-8)
- Lenalidomide Impurity 8 (CAS 2197414-55-2)
- Lenalidomide Impurity 56 (CAS 1421593-78-3)
- Lenalidomide Impurity 6 (CAS 2717380-87-3)
- Lenalidomide Impurity 67 (CAS CATO-C4X-190367)
- Lenalidomide Impurity 68 (CAS CATO-C4X-190368)
- Lenalidomide Impurity 69 (CAS CATO-C4X-190369)
Recommended Standards
- Allopurinol Impurity 7 (CAS 321571-07-7)
- Imidapril Impurity 7 (CAS 168292-63-5)
- Allopurinol Impurity 32 (CAS 52632-17-4)
- Cyclohexanone 2,4-Dinitrophenylhydrazone (CAS 1589-62-4)
- Palbociclib Impurity 4 (CAS 1774897-13-0)
- Esomeprazole Impurity 72 (CAS CATO-C4X-111272)
- Cefpodoxime Proxetil Impurity 29 (CAS CATO-C4X-157929)
- 5-Bromo-3-ethylthiophene-2-carboxylic acid (CAS 193064-97-0)
- 2-chloro-4-ethynyl-1-methoxybenzene (CAS 120136-29-0)
- 4-[(6-methyl-4-oxo-1,4-dihydropyrimidin-2-yl)sulfanyl]-3-nitrobenzoic acid (CAS 710315-25-6)
- 1,7,8-Trichlorodibenzo-p-dioxin (CAS 82306-65-8)
- 7-Fluoro-3h-spiro[benzofuran-2,4'-piperidine] hydrochloride (CAS 2680614-86-0)
- 2-(5-Ethyl-2,4-dimethyl-6-oxopyrimidin-1(6H)-yl)acetic acid (CAS 1708178-79-3)
- D-Ser39-Tirzepatide (CAS CATO-CPTD788694)
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