Methyl 5-Bromo-6-fluoroindole-2-carboxylate CAS 2006277-60-5
| CAS No. | 2006277-60-5 |
| Molecular Formula | C10H7BrFNO2 |
| Molecular Weight | 272.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 5-Bromo-6-fluoroindole-2-carboxylate.
Methyl 5-Bromo-6-fluoroindole-2-carboxylate (CAS 2006277-60-5) is a high-purity analytical reference standard with the molecular formula C10H7BrFNO2 and a molecular weight of 272.07 g/mol.
Based on its molecular formula C10H7BrFNO2, Methyl 5-Bromo-6-fluoroindole-2-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 272.07 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 5-Bromo-6-fluoroindole-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7BrFNO2 |
| Molecular Weight | 272.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 5-Bromo-7-fluoroindole-3-acetic Acid (CAS 1019111-81-9)
- 2-(4-Bromo-2-fluorophenyl)-1,2-dihydro-5-methyl-3H-1,2,4-triazol-3-one (CAS 111992-09-7)
- 4-Bromo-2,3-difluorobenzenesulfonamide (CAS 1133123-01-9)
- 2-(7-Bromo-4-fluoro-1H-indol-3-yl)acetic acid (CAS 1227496-22-1)
- 2-(6-Bromo-4-fluoro-1H-indol-3-yl)acetic acid (CAS 1227502-64-8)
- 2-(6-Bromo-5-fluoro-1H-indol-3-yl)acetic acid (CAS 1227563-84-9)
- 2-(5-Bromo-6-fluoro-1H-indol-3-yl)acetic acid (CAS 1227576-93-3)
- 4-Bromo-7-fluoroindole-3-acetic Acid (CAS 1227598-12-0)
Recommended Standards
- Methyl 4-bromo-6-fluoro-1H-indole-2-carboxylate (CAS 476618-03-8)
- Methyl 6-bromo-4-fluoro-1h-indole-2-carboxylate (CAS 926249-89-0)
- Methyl 3-bromo-5-fluoro-1H-indole-6-carboxylate (CAS 2227205-24-3)
- Methyl 7-bromo-6-fluoro-1H-indole-2-carboxylate (CAS 2092716-68-0)
- Methyl 2-[4-(4-bromobenzenesulfonyl)-3,4-dihydro-2H-1,4-benzoxazin-3-yl]acetate (CAS 865657-63-2)
- Butyl 4-(3-bromophenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 5473-80-3)
- 2-Methyl-6-(methylthio)phenol (CAS 25674-55-9)
- 2-Bromo-1-(bromomethyl)-3-nitrobenzene (CAS 82617-49-0)
- (S)-Methyl 2-amino-3-(4-(trifluoromethyl)phenyl)propanoate hydrochloride (CAS 123023-03-0)
- 3,3,4,4,4-Pentafluorobutan-1-ol (CAS 54949-74-5)
- Tofacitinib Impurity 241 (CAS CATO-C4X-1079241)
- 4-Chloro-6-(trifluoromethyl)quinoline-3-carbonitrile (CAS 1017788-96-3)
- Regadenoson Impurity 21 (CAS 146-77-0)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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