5-((4-Chlorophenyl)sulfonyl)-3-methyl-1,2,4-thiadiazole CAS 20064-40-8
| CAS No. | 20064-40-8 |
| Molecular Formula | C9H7ClN2O2S2 |
| Molecular Weight | 274.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-((4-Chlorophenyl)sulfonyl)-3-methyl-1,2,4-thiadiazole (CAS 20064-40-8), molecular formula C9H7ClN2O2S2 and molecular weight 274.75 g/mol, is a CATO reference standard with documented purity and traceability.
5-((4-Chlorophenyl)sulfonyl)-3-methyl-1,2,4-thiadiazole (C9H7ClN2O2S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H7ClN2O2S2 |
| Molecular Weight | 274.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 1243060-93-6 2-(4-Chlorophenyl)-4-piperazin-1-ylpyrimidine MFCD15732439 (CAS 1243060-93-6)
- 3-(2-Chlorophenyl)-6-(piperazin-1-yl)pyridazine (CAS 1338664-16-6)
- 4-(4-Chlorophenyl)-5-(methylsulfonyl)-1,2,3-thiadiazole (CAS 1708037-23-3)
- 4-(3-Chlorophenyl)-5-(methylsulfonyl)-1,2,3-thiadiazole (CAS 1713655-95-8)
- 2-(4-chlorophenyl)-1,3-thiazole-4-sulfonamide (CAS 1803581-26-1)
- 2-(4-Chlorophenyl)-5-(methylsulfonyl)-1,3,4-thiadiazole (CAS 63857-87-4)
- 3-(4-Chlorophenyl)-6-piperazin-1-ylpyridazine (CAS 933693-20-0)
- 5-(1-(4-Chlorophenyl)-2-methylprop-1-en-1-yl)pyrimidine-4,6-diamine (CAS 27398-41-0)
Recommended Standards
- 4-Chloro-N-(thiazol-2-yl)benzenesulfonamide (CAS 99067-53-5)
- 4-Benzyl-8-chloro-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine (CAS 956431-23-5)
- 5-(4-Chlorobenzenesulfonyl)-4-methyl-1,2,3-thiadiazole (CAS 339008-83-2)
- 3-Amino-4-chloro-N-(3,5-dimethylphenyl)benzamide (CAS 723291-69-8)
- N-cyclopropyl-5-fluoropyridin-2-amine (CAS 1251244-04-8)
- 5-Amino-2-phenyl-1H-1,2,4-triazol-3(2H)-one (CAS 29472-94-4)
- (2,3-Difluoro-4-(4-methylpiperidin-1-yl)phenyl)boronic acid (CAS 1704069-62-4)
- N-(4-Methoxyphenyl)-N-methylquinolin-4-amine (CAS 827030-95-5)
- Faropenem Impurity 46 (CAS CATO-C4X-128946)
- tert-Butyl 4-hydroxycyclohexanecarboxylate (CAS 220179-93-1)
- (2S,3R)-3-(cyclopentylmethyl)-N-hydroxy-4-oxo-4-(1-piperidinyl)-2-[(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)methyl]butanamide (2S,3R)-3-(cyclopentylmethyl)-N-oxidanyl-4-oxidanylidene-4-piperidin-1-yl-2-[[3,4,4-trimethyl-2,5-bis(oxidanylidene)imidazolidin-1-yl]methyl]butanamide 2182-55-0 A815685 (CAS 2182-55-0)
- (2R,3R)-2-Benzyl-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole (CAS 1884457-36-6)
- N1-[(1E)-(2-Methoxyphenyl)methylene]-4-phenyl-1H-imidazole-1,2-diamine (CAS 1993501-23-7)
- Peptide 431 (CAS CATO-CPTD788431)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com