Ethyl 2-fluoro-2-(triphenylphosphoranylidene)acetate CAS 201221-71-8
| CAS No. | 201221-71-8 |
| Molecular Formula | C22H20FO2P |
| Molecular Weight | 366.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-fluoro-2-(triphenylphosphoranylidene)acetate.
Ethyl 2-fluoro-2-(triphenylphosphoranylidene)acetate (CAS 201221-71-8), molecular formula C22H20FO2P and molecular weight 366.37 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, organophosphorus functionality, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 2-fluoro-2-(triphenylphosphoranylidene)acetate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 366.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 2-fluoro-2-(triphenylphosphoranylidene)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H20FO2P |
| Molecular Weight | 366.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | F-containing |
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Recommended Standards
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- 2,5-Dimethylphenyl cyclohexanecarboxylate (CAS 666212-79-9)
- Gemcitabine Impurity 16 (CAS CATO-C4X-137216)
- Propyl 2-[1-(2-bromoacetyl)-3-oxo-2-piperazinyl]-acetate (CAS 1219402-10-4)
- 7H-Pyrrolo[2,3-d]pyrimidine-4,6-diol (CAS 89488-03-9)
- 5-(tert-Butylthio)-N,N,6-trimethylpyridin-2-amine (CAS 1355200-91-7)
- 2,5-Dibromo-3-(difluoromethoxy)aniline (CAS 1804512-92-2)
- Human glucagon CRS (CAS 9007-92-5)
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