Papaverine Impurity 28 CAS 20122-48-9
| CAS No. | 20122-48-9 |
| Molecular Formula | C20H21NO4 |
| Molecular Weight | 339.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Papaverine Impurity 28 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 339.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Papaverine Impurity 28 (CAS 20122-48-9) is a certified pharmaceutical impurity reference standard with the molecular formula C20H21NO4 and a molecular weight of 339.39 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Papaverine Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21NO4 |
| Molecular Weight | 339.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Related Papaverine Standards
- Papaverine (CAS 58-74-2)
- Papaverine-d3 Hydrochloride (CAS 113718-66-4)
- Papaverine Hydrochloride - Impurity E (CAS 13074-31-2)
- Papaverine Impurity 26 (CAS CATO-C4X-206726)
- Papaverine Impurity 39 (CAS 75608-42-3)
- Papaverine Impurity 40 (CAS 361389-65-3)
- Papaverine Impurity 42 (CAS CATO-C4X-206742)
- Papaverine impurity 24 (CAS 33490-73-2)
Recommended Standards
- Ruxolitinib Impurity 84 (CAS CATO-C4X-205884)
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- Tetrahydroberberine (CAS 522-97-4)
- Milrinone impurity 39 (CAS CATO-C4X-109139)
- Pitavastatin Impurity 29 (CAS CATO-C4X-103729)
- Obeticholic Acid Impurity 3 (CAS 1708092-13-0)
- 3-Amino-N-(3-chloro-2-methylphenyl)-4-(2-chlorophenyl)-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 444156-88-1)
- 3-Methylpentane (CAS 96-14-0)
- Ethyl thiophene-2-carbimidate (CAS 54610-47-8)
- Degarelix-d7 (CAS 214766-78-6（unlabelled）)
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