1-Fluoropyrrolidine-2,5-dione CAS 201281-58-5
| CAS No. | 201281-58-5 |
| Molecular Formula | C4H4FNO2 |
| Molecular Weight | 117.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Fluoropyrrolidine-2,5-dione (C4H4FNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 1-Fluoropyrrolidine-2,5-dione (CAS 201281-58-5), a certified reference material (molecular formula C4H4FNO2, MW 117.08 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H4FNO2 |
| Molecular Weight | 117.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoropyrrolidine Standards
- 3-Ethyl-3-fluoropyrrolidine (CAS 1554559-61-3)
- 3-Fluoropyrrolidine-3-carbonitrile (CAS 1363594-93-7)
- 3-Fluoropyrrolidine-3-carboxamide (CAS 1784135-63-2)
- (2S)-4-Fluoropyrrolidine-2-carboxamide (CAS 556834-92-5)
- 4-Fluoropyrrolidine-2-carboxamide (CAS 934972-82-4)
- 3-fluoropyrrolidine-3-carboxylic acid (CAS 1228634-93-2)
- (2R)-3-fluoropyrrolidine-2-carboxylic acid (CAS 1315056-15-5)
- 3-Fluoropyrrolidine-2-carboxylic acid (CAS 1423029-33-7)
Recommended Standards
- 5,6-Dihydro Uracil- (CAS 181516-96-1)
- Ethyl cyanide-<SUP>13</SUP>C,<SUP>15</SUP>N-acetate-1,2-<SUP>13</SUP>C<SUB>2</SUB> (CAS 1196157-67-1)
- 4-Fluoro-5-methylisoxazol-3(2H)-one (CAS 131573-78-9)
- 2-(Dimethylphosphoryl)acetonitrile (CAS 89630-50-2)
- 7,7-Bis(4-(diethylamino)-2-ethoxyphenyl)furo[3,4-b]pyridin-5(7H)-one (CAS 132467-74-4)
- 3-Bromo-2-piperazinopyridine (CAS 87394-56-7)
- 1-(Benzo[d]thiazol-2-yl)-N-methylmethanamine dihydrochloride (CAS 2103398-81-6)
- N-(m-Toluoyl)glycine (CAS 27115-49-7)
- Cyclopropyl(naphthalen-1-yl)methanamine hydrochloride (CAS 58271-60-6)
- 2-(Chloromethyl)-5-(2-fluorophenyl)-1,3,4-oxadiazole (CAS 350672-17-2)
- 2-(1-Aminocyclobutyl)acetic Acid Hydrochloride (CAS 1335042-49-3)
- 2-((5-((Naphthalen-1-yloxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 383145-92-4)
- 2,5-Difluoro-1,4-Benzenediboronic Acid Bis(pinacol) Ester (CAS 303006-90-8)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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