(2S)-4-Fluoropyrrolidine-2-carboxamide CAS 556834-92-5

Purity 97%+In StockPharmaceutical Standards
CAS No.556834-92-5
Molecular FormulaC5H9FN2O
Molecular Weight132.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2S)-4-Fluoropyrrolidine-2-carboxamide CAS 556834-92-5 chemical structure

Description

(2S)-4-Fluoropyrrolidine-2-carboxamide (CAS 556834-92-5) is a high-purity analytical reference standard with the molecular formula C5H9FN2O and a molecular weight of 132.14 g/mol.

The molecular framework of (2S)-4-Fluoropyrrolidine-2-carboxamide (C5H9FN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC5H9FN2O
Molecular Weight132.14 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1984
Halogen ContentF-containing
Nitrogen Atoms2

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