2-Chloro-1-(1H-indazol-1-yl)propan-1-one CAS 201299-94-7
| CAS No. | 201299-94-7 |
| Molecular Formula | C10H9ClN2O |
| Molecular Weight | 208.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-1-(1H-indazol-1-yl)propan-1-one (CAS 201299-94-7), molecular formula C10H9ClN2O and molecular weight 208.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-1-(1H-indazol-1-yl)propan-1-one (C10H9ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9ClN2O |
| Molecular Weight | 208.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-2-(1-methyl-1,4-dihydropyridin-4-ylidene)-3-oxobutanenitrile (CAS 1000932-32-0)
- 2-chloro-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}propan-1-one (CAS 1037152-84-3)
- 2-(5-Chloro-1H-indol-3-yl)acetamide (CAS 1044772-39-5)
- N-(4-chloro-1H-indol-6-yl)acetamide (CAS 1082041-66-4)
- 2-(Chloro(phenyl)methyl)-5-methyl-1,3,4-oxadiazole (CAS 1094378-62-7)
- 4-Chloro-6,7,8,9-tetrahydrobenzofuro[3,2-d]pyrimidine (CAS 1132690-77-7)
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Recommended Standards
- 2-Benzyl-5-(chloromethyl)-1,3,4-oxadiazole (CAS 36646-13-6)
- 2-Chloro-1-(2-methyl-1Hbenzimidazol-1-yl)-ethanone (CAS 901346-69-8)
- 2-(Chloromethyl)-9-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 796067-44-2)
- 2-Chloro-1-fluoro-4-(methylsulfonyl)benzene (CAS 847148-17-8)
- Ortho Chloro Levocetrizine (CAS 5267-36-7)
- 8-(Tert-butyl) 3-ethyl 8-azabicyclo[3.2.1]Octane-3,8-dicarboxylate (CAS 1246644-52-9)
- 1-(4-Chlorophenyl)cyclobutane-1-carbaldehyde (CAS 106079-12-3)
- 3-(3,5-Dibromo-4-hydroxyphenyl)-3-phenylisobenzofuran-1(3H)-one (CAS 6315-70-4)
- 1-[4-(6-hydroxyhex-1-ynyl)phenyl]hexahydropyrimidine-2,4-dione (CAS 2904664-77-1)
- Dibutyl furan-3,4-dicarboxylate (CAS 107821-61-4)
- 6-Amino-1-methyl-5,6,7,8-tetrahydroquinolin-2(1H)-one (CAS 1422142-23-1)
- N-(4-Methyl-2-phenylpyrimidin-5-yl)benzamide (CAS 649746-01-0)
- Methyl 3-methoxyazetidine-3-carboxylate (CAS 1392879-17-2)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
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