1-Bromo-5-chloro-3-fluoro-2-iodobenzene CAS 201849-16-3
| CAS No. | 201849-16-3 |
| Molecular Formula | C6H2BrClFI |
| Molecular Weight | 335.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-Bromo-5-chloro-3-fluoro-2-iodobenzene (CAS 201849-16-3) is a high-purity analytical reference standard with the molecular formula C6H2BrClFI and a molecular weight of 335.34 g/mol.
The molecular framework of 1-Bromo-5-chloro-3-fluoro-2-iodobenzene (C6H2BrClFI) is characterized by fluorine/chlorine/bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H2BrClFI |
| Molecular Weight | 335.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | F/Cl/Br/I-containing |
Related Bromo Standards
- 4-Bromo-2-chloro-5-fluoroiodobenzene (CAS 1000572-73-5)
- 1-Bromo-2-chloro-3-fluoro-4-iodobenzene (CAS 1000573-03-4)
- 1-Bromo-3-chloro-5-fluoro-2-iodobenzene (CAS 1000577-66-1)
- 1-Bromo-5-chloro-4-fluoro-2-iodobenzene (CAS 1067882-65-8)
- 1-Bromo-2-chloro-5-fluoro-4-iodobenzene (CAS 1160574-56-0)
- 1-Bromo-4-chloro-5-fluoro-2-iodobenzene (CAS 1263377-64-5)
- 1-Bromo-3-chloro-2-fluoro-5-iodobenzene (CAS 1416241-38-7)
- 1-Bromo-4-chloro-2-fluoro-3-iodobenzene (CAS 1820641-80-2)
Recommended Standards
- 1-Bromo-5-chloro-2-fluoro-3-iodobenzene (CAS 2135861-24-2)
- 1-Methyl-2-((3-(trifluoromethyl)phenyl)thio)-1H-indole-3-carbaldehyde (CAS 338416-52-7)
- 1-Bromo-4-chloro-2-fluoro-5-iodobenzene (CAS 2386089-00-3)
- 2-((4-Amino-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 869068-37-1)
- (3R,4S,5S)-3-Amino-5-(10H-phenoxazin-10-yl)tetrahydro-2H-pyran-4-ol (CAS 2088957-22-4)
- 2-Amino-1-(4-fluorophenyl)ethan-1-one (CAS 369-43-7)
- 2-Chloro-4,5,6-trifluorobenzo[d]thiazole (CAS 1245213-27-7)
- Methyl(4-methylbenzyl)sulfane (CAS 5925-57-5)
- 2-Bromo-4,6-difluorobenzaldehyde (CAS 154650-59-6)
- 6-(2-Hydroxyethyl)-2-(isopropylthio)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one (CAS 1708079-93-9)
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- N-Ethyl-2-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1256359-87-1)
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