Paroxetine Impurity 48 CAS 201855-60-9
| CAS No. | 201855-60-9 |
| Molecular Formula | C19H22FNO |
| Molecular Weight | 299.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Paroxetine Impurity 48 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Paroxetine Impurity 48 (CAS 201855-60-9) is a certified pharmaceutical impurity reference standard with the molecular formula C19H22FNO and a molecular weight of 299.38 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Paroxetine Impurity 48 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 299.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H22FNO |
| Molecular Weight | 299.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 26 (CAS 608521-21-7)
- Paroxetine Impurity 56 (CAS 202534-94-9)
- Paroxetine Impurity N29 (CAS 324024-00-2)
- Paroxetine Impurity 26 (CAS 324023-99-6)
- Paroxetine Impurity 70 (CAS 1396174-70-1)
- Paroxetine (CAS 61869-08-7)
- Paroxetine 3-Hydroxy Metabolite (CAS 112058-89-6)
- Paroxetine 4-Hydroxy Metabolite (CAS 112058-90-9)
Recommended Standards
- 3-((4-(Sec-butyl)phenyl)amino)-1-(4-fluorophenyl)propan-1-one (CAS 882748-27-8)
- N-(2,5-Dimethylphenylsulfonyl)-DL-leucine (CAS 1009793-82-1)
- 1-Benzyl-4-(2-fluorobenzyl)piperidin-4-ol (CAS 71916-70-6)
- N,N-Dimethyl-2-((2-phenyl-1H-purin-6-yl)thio)ethanamine (CAS 106823-66-9)
- Oseltamivir impurity 232 (CAS CATO-C4X-1720232)
- Doxofylline Impurity 39 (CAS CATO-C4X-151339)
- Gadoteridol impurity 30 (CAS 2172857-50-8)
- 6-Bromo-3-fluoro-2-hydroxybenzoic acid (CAS 1784095-53-9)
- Regadenoson Impurity D (CAS 1154383-52-4)
- tert-Butyl 2-amino-4-((S)-sec-butyl)-4H-pyrrolo[3,4-d]thiazole-5(6H)-carboxylate (CAS 1957130-55-0)
- 4-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-yl)benzohydrazide (CAS 952183-14-1)
- 3-(1-Chloro-2-(methylamino)ethyl)phenol (CAS 119610-61-6)
- 2-(7-Methoxy-1-benzofuran-3-yl)acetic acid (CAS 79477-01-3)
- Dendroaspis Natriuretic Peptide (CAS 255721-52-9)
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