Paroxetine Impurity N29 CAS 324024-00-2
| CAS No. | 324024-00-2 |
| Molecular Formula | C19H21NO3 |
| Molecular Weight | 311.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Paroxetine Impurity N29.
Paroxetine Impurity N29 (CAS 324024-00-2) is a certified pharmaceutical impurity reference standard with the molecular formula C19H21NO3 and a molecular weight of 311.37 g/mol.
Paroxetine Impurity N29 (C19H21NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21NO3 |
| Molecular Weight | 311.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 26 (CAS 608521-21-7)
- Paroxetine Impurity 48 (CAS 201855-60-9)
- Paroxetine Impurity 26 (CAS 324023-99-6)
- Paroxetine Impurity 70 (CAS 1396174-70-1)
- Paroxetine (CAS 61869-08-7)
- Paroxetine Impurity 56 (CAS 202534-94-9)
- Paroxetine 3-Hydroxy Metabolite (CAS 112058-89-6)
- Paroxetine 4-Hydroxy Metabolite (CAS 112058-90-9)
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