4-Amino-6-bromo-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide CAS 20201-56-3
| CAS No. | 20201-56-3 |
| Molecular Formula | C12H14BrN5O5 |
| Molecular Weight | 388.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 4-Amino-6-bromo-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide (C12H14BrN5O5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 388.17 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-Amino-6-bromo-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide (CAS 20201-56-3), molecular formula C12H14BrN5O5 and molecular weight 388.17 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Amino-6-bromo-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14BrN5O5 |
| Molecular Weight | 388.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
Related Amino Standards
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- 2-Amino-3-[(E)-{[4-(benzyloxy)phenyl]methylidene}amino]-6-(trifluoromethyl)-3,4-dihydropyrimidin-4-one (CAS 866145-95-1)
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Recommended Standards
- 4-(6-Bromo-2-oxo-2H-chromene-3-amido)benzoic acid (CAS 312756-47-1)
- 5-(3,4-Dichlorophenyl)-3-{[3-(trifluoromethyl)phenoxy]methyl}-1,2-oxazole (CAS 339019-85-1)
- 1-Methyl-1H-indole-2,3-dione 3-{N-[2,6-dichloro-4-(trifluoromethyl)phenyl]hydrazone} (CAS 320422-23-9)
- (4-Iodophenyl)diphenylphosphane (CAS 440111-10-4)
- 2-{[(5-bromo-2-fluorophenyl)methyl]amino}ethan-1-ol (CAS 1152522-37-6)
- 2-(Trifluoromethyl)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine dihydrochloride (CAS 1956328-49-6)
- 7-Cyano-3-iodo-5-azaindole (CAS 1352395-49-3)
- N-(3-Amino-4-chlorophenyl)-2-(2-isopropyl-5-methylphenoxy)acetamide (CAS 1020054-45-8)
- 5-Bromo-2-(piperidin-3-ylmethoxy)pyridine (CAS 1247532-03-1)
- Atomoxetine Impurity 38 (CAS 29869-74-7)
- 3-(Piperidin-4-ylmethyl)-1H-indole (CAS 3515-49-9)
- 3-Fluoro-4-methoxy-alpha-(trifluoromethyl)benzyl Alcohol (CAS 1307165-89-4)
- Nebivolol Impurity 62 (CAS CATO-C4X-196862)
- Retatrutide (CAS 2381089-83-2)
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