1-Methyl-1H-indole-2,3-dione 3-{N-[2,6-dichloro-4-(trifluoromethyl)phenyl]hydrazone} CAS 320422-23-9
| CAS No. | 320422-23-9 |
| Molecular Formula | C16H10Cl2F3N3O |
| Molecular Weight | 388.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Methyl-1H-indole-2,3-dione 3-{N-[2,6-dichloro-4-(trifluoromethyl)phenyl]hydrazone} (C16H10Cl2F3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1-Methyl-1H-indole-2,3-dione 3-{N-[2,6-dichloro-4-(trifluoromethyl)phenyl]hydrazone} (CAS 320422-23-9), molecular formula C16H10Cl2F3N3O and molecular weight 388.17 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H10Cl2F3N3O |
| Molecular Weight | 388.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- Diethyl 2-(2-bromo-4-nitrobenzoyl)malonate (CAS 1329166-67-7)
- 4-(6-Bromo-2-oxo-2H-chromene-3-amido)benzoic acid (CAS 312756-47-1)
- tert-Butyl 3-iodo-5-nitro-1H-indole-1-carboxylate (CAS 914349-32-9)
- 4-Amino-6-bromo-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide (CAS 20201-56-3)
- Methyl 6-fluoro-2-methylquinoline-4-carboxylate (CAS 917777-71-0)
- 4-(Dimethylamino)-3-formylbenzoic acid hydrochloride (CAS 2126178-16-1)
- 6-Bromo-4-fluoropyridazin-3-amine (CAS 2386479-09-8)
- 4-Chloro-5-cyclopropoxy-N,N-dimethylpicolinamide (CAS 1243405-70-0)
- Tert-butyl 3-cyano-9-azabicyclo[3.3.1]Nonane-9-carboxylate (CAS 2167329-04-4)
- (R)-3-Hydroxy-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one (CAS 608148-60-3)
- Oxymorphone in Methanol(Solution) (CAS 76-41-5)
- 4-Methoxy-2,5-dimethylpyridine 1-oxide (CAS 116419-03-5)
- 4-Ethoxy-2-methoxyaniline (CAS 127285-30-7)
- Integrin Binding Peptide trifluoroacetate salt (CAS 278792-07-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com